CAJ | 학술논문

甲状腺激素及相关抗体在乳腺癌疾病发展过程中具有一定作用,可能的机制包括碘复合物抑制乳腺细胞增殖和促进其凋亡；甲状腺激素可影响乳腺癌细胞的增殖与凋亡；甲状腺激素与雌激素的比例失调,促进乳腺细胞癌变；甲减可影响乳腺肿瘤细胞的增殖和侵袭力；甲状腺疾病时淋巴细胞浸润或局部免疫反应异常等.
갑상선격소급상관항체재유선암질병발전과정중구유일정작용,가능적궤제포괄전복합물억제유선세포증식화촉진기조망；갑상선격소가영향유선암세포적증식여조망；갑상선격소여자격소적비례실조,촉진유선세포암변；갑감가영향유선종류세포적증식화침습력；갑상선질병시림파세포침윤혹국부면역반응이상등.
Thyroid hormones and the related antibodies have some function in the natural process of breast cancer development.The possible mechanisms include:iodine complex can inhibit breast cell proliferation and can induce apoptosis; thyroid hormone can affect breast cancer cell proliferation and apoptosis; the imbalance of thyroid hormone and estrogen hormone promotes breast cells cancerous; hypothyroidism may affect the proliferation and invasiveness of breast tumors; lymphocytic infiltration or abnormal local immune response in thyroid disease.