CAJ | 학술논문

目前非小细胞肺癌(NSCLC)发生、发展及转移机制的研究不断深入,关于NSCLC中Fas及Fas配体(FasL)蛋白的表达以及其介导的凋亡、免疫逃逸在肺癌发生发展、转移及预后中的作用机制研究不断涌现.探讨Fas-FasL系统在NSCLC发生发展中所起的作用,可为临床早期诊断肺癌、判断预后、设计新的治疗策略提供依据.
목전비소세포폐암(NSCLC)발생、발전급전이궤제적연구불단심입,관우NSCLC중Fas급Fas배체(FasL)단백적표체이급기개도적조망、면역도일재폐암발생발전、전이급예후중적작용궤제연구불단용현.탐토Fas-FasL계통재NSCLC발생발전중소기적작용,가위림상조기진단폐암、판단예후、설계신적치료책략제공의거.
With the rapid growth of incidence of non-small cell lung cancer (NSCLC),more and more studies have been made about its occurrence,development and metastatic mechanism m recent years.Researches about Fas/FasL protein expression and Fas/FasL-mediated apoptosis,immune escape mechanism and their roles in the pathogenesis,progression and prognosis of lung cancer are constantly emerging.Discussion about the roles of Fas/ FasL system in NSCLC could provide evidence for early diagnosis,prognosis prediction and new treatment of NSCLC.