国际肿瘤学杂志
國際腫瘤學雜誌
국제종류학잡지
JOURNAL OF INTERNATIONAL ONCOLOGY
2013年
6期
469-471
,共3页
涂庆峰%王秀丽%石磊%王宏伟
塗慶峰%王秀麗%石磊%王宏偉
도경봉%왕수려%석뢰%왕굉위
光动力疗法%光敏感药%药物载体%肿瘤
光動力療法%光敏感藥%藥物載體%腫瘤
광동력요법%광민감약%약물재체%종류
Photodynamic therapy%Photosensitizer%Drug carriers%Neoplasms
诸多体内外实验证明,通过运用适宜的药物运载体系既可以增加光敏剂的稳定性,也可以促进光敏剂在肿瘤组织中聚集,提高光动力治疗的靶向性,加深其作用深度和单态氧的产出率,并能减少不良反应.所以新型光敏剂药物运载体系的研究在光动力治疗肿瘤中拥有重要的应用价值.
諸多體內外實驗證明,通過運用適宜的藥物運載體繫既可以增加光敏劑的穩定性,也可以促進光敏劑在腫瘤組織中聚集,提高光動力治療的靶嚮性,加深其作用深度和單態氧的產齣率,併能減少不良反應.所以新型光敏劑藥物運載體繫的研究在光動力治療腫瘤中擁有重要的應用價值.
제다체내외실험증명,통과운용괄의적약물운재체계기가이증가광민제적은정성,야가이촉진광민제재종류조직중취집,제고광동력치료적파향성,가심기작용심도화단태양적산출솔,병능감소불량반응.소이신형광민제약물운재체계적연구재광동력치료종류중옹유중요적응용개치.
In vitro or in vivo results of investigations into the development of photosensitizer drug delivery systems have demonstrated that the use of vehicles not only enhance the stability of photosensitizer,but also promote the accumulation of photosensitizer in tumor tissue,enhance the targetability of photodynamic therapy,the working depth,the yield of singlet oxygen and overcome many untoward effects.So the research of new photosensitizer drug delivery system has important application value in photodynamic therapy of tumor.