国际肿瘤学杂志
國際腫瘤學雜誌
국제종류학잡지
JOURNAL OF INTERNATIONAL ONCOLOGY
2013年
9期
643-645
,共3页
肿瘤%胸苷激酶%免疫组织化学
腫瘤%胸苷激酶%免疫組織化學
종류%흉감격매%면역조직화학
Neoplasms%Thymidine kinase%Immunohistochemistry
胸苷激酶1(TK1)是一种嘧啶补救途径的激酶,能催化脱氧胸苷磷酸化为一腺胸苷酸,与细胞周期调控和细胞增殖密切相关.多项试验表明,TK1可用于健康体检、肿瘤筛查、常规检测、疗效监视和预后评估,是一种灵敏有效地评估人体肿瘤增长的标志物.
胸苷激酶1(TK1)是一種嘧啶補救途徑的激酶,能催化脫氧胸苷燐痠化為一腺胸苷痠,與細胞週期調控和細胞增殖密切相關.多項試驗錶明,TK1可用于健康體檢、腫瘤篩查、常規檢測、療效鑑視和預後評估,是一種靈敏有效地評估人體腫瘤增長的標誌物.
흉감격매1(TK1)시일충밀정보구도경적격매,능최화탈양흉감린산화위일선흉감산,여세포주기조공화세포증식밀절상관.다항시험표명,TK1가용우건강체검、종류사사、상규검측、료효감시화예후평고,시일충령민유효지평고인체종류증장적표지물.
Thymidine kinase 1 (TK1),an enzyme of the pyrimidine remedial pathway,can catalyze phosphorylation of thymidine to thymidine monophosphate.It is closely related to cell cycle regulation and cell proliferation.A number of experiments show that TK1 can be used for physical examination,tumor screening,routine testing,effect monitoring and prognosis evaluation,which is considered to be a sensitive and useful marker for human tumor growth.