CAJ | 학술논문

局部晚期非小细胞肺癌(NSCLC)非手术治疗的标准手段为同步放化疗.同步放化疗中常用的化疗方案有EP方案、NP方案、DC方案及PC方案.新药联合方案及靶向治疗目前仍处于研究阶段.老年患者的耐受性下降,但并非同步放化疗的绝对禁忌人群.超分割及高剂量放疗虽然耐受性尚可,但其有效性及远期不良反应仍需进一步研究和评估.
국부만기비소세포폐암(NSCLC)비수술치료적표준수단위동보방화료.동보방화료중상용적화료방안유EP방안、NP방안、DC방안급PC방안.신약연합방안급파향치료목전잉처우연구계단.노년환자적내수성하강,단병비동보방화료적절대금기인군.초분할급고제량방료수연내수성상가,단기유효성급원기불량반응잉수진일보연구화평고.
The standard non-surgery approach for locally advanced non-small cell lung cancer (NSCLC) is concurrent chemoradiotherapy.Common chemotherapy regimens include EP,NP,DC and PC.New chemotherapy drugs combination and targeted therapy are still under study.The tolerances of elderly patients are declining for concurrent chemoradiotherapy,but it is not the absolute contraindication.The tolerance for hyperfraction and high dose radiotherapy is well,however,the effectiveness and long-term toxicity need to be further studied and evaluated.