国际肿瘤学杂志
國際腫瘤學雜誌
국제종류학잡지
JOURNAL OF INTERNATIONAL ONCOLOGY
2013年
12期
905-907
,共3页
锌指%同源盒结构域蛋白质类%肿瘤%转录因子
鋅指%同源盒結構域蛋白質類%腫瘤%轉錄因子
자지%동원합결구역단백질류%종류%전록인자
Zinc fingers%Homeodomain proteins%Neoplasms%Transcription factors
转录抑制因子ZHX2是ZHX蛋白家族的成员之一,在人体组织中广泛存在,通过转录抑制作用参与多种疾病的发生与发展.研究表明ZHX2与肝癌、多发性骨髓瘤、胃癌、结直肠癌等的发生发展密切相关,具有肿瘤治疗的潜在价值.
轉錄抑製因子ZHX2是ZHX蛋白傢族的成員之一,在人體組織中廣汎存在,通過轉錄抑製作用參與多種疾病的髮生與髮展.研究錶明ZHX2與肝癌、多髮性骨髓瘤、胃癌、結直腸癌等的髮生髮展密切相關,具有腫瘤治療的潛在價值.
전록억제인자ZHX2시ZHX단백가족적성원지일,재인체조직중엄범존재,통과전록억제작용삼여다충질병적발생여발전.연구표명ZHX2여간암、다발성골수류、위암、결직장암등적발생발전밀절상관,구유종류치료적잠재개치.
Transcription repressor ZHX2 is one of the members in ZHX protein family,which exists widely in human tissue and participates in the occurrence and development of various diseases.Researches show that ZHX2 is closely related to the occurrence and development of cancers,such as liver cancer,multiple myeloma,gastric cancer and colorectal cancer,which has the potential value of tumor treatment.
