CAJ | 학술논문

多药耐药性是导致乳腺癌化疗失败的重要原因之一,其发生机制非常复杂,涉及到药物在体内的转运、代谢、作用靶点等多个方面.近年来研究发现中药制剂不仅在提高患者抵抗力改善患者一般状态,增敏放化疗效果方面有良好的作用,而且在逆转乳腺癌多药耐药方面也有重要作用.
다약내약성시도치유선암화료실패적중요원인지일,기발생궤제비상복잡,섭급도약물재체내적전운、대사、작용파점등다개방면.근년래연구발현중약제제불부재제고환자저항력개선환자일반상태,증민방화료효과방면유량호적작용,이차재역전유선암다약내약방면야유중요작용.
Multi-drug resistance of breast cancer remains a major obstacle for effective treatment,which involves many complicated mechanisms,including drug transport in the body,metabolism and drug targets.Recent researches find that the tradition Chinese medicine not only has good effects in improving the body resistance and general situation of patients and enhancing the effects of chemoradiotherapy,but also plays a vital roles in the muti-drug resistance reversal of breast cancer.