CAJ | 학술논문

ⅢA(N2)期非小细胞肺癌预后因素繁多,与其预后相关的组织学分子标志物主要有多药耐药基因、生长因子类、黏蛋白4、胰岛素样生长因子-2、增殖细胞核抗原以及磷酸酶-张力蛋白酶等.这些基因的不同表达或许可以把N2期非小细胞肺癌分成不同的分子亚型,从而更有效地指导临床.
ⅢA(N2)기비소세포폐암예후인소번다,여기예후상관적조직학분자표지물주요유다약내약기인、생장인자류、점단백4、이도소양생장인자-2、증식세포핵항원이급린산매-장력단백매등.저사기인적불동표체혹허가이파N2기비소세포폐암분성불동적분자아형,종이경유효지지도림상.
Prognosis factors of Ⅲ A (N2) phase non-small cell lung cancer are various.The histological molecular markers are mainly about multi-resistant gene,growth factors,mucin 4,insulin-like growth factor-2,Ki-67,PTEN and so on.Different expressions of these genes may divide the N2 non-small-cell lung cancer into different molecular subtypes,which is more effective to guide clinical therapy.