CAJ | 학술논문

放疗是无手术指征肝细胞肝癌(HCC)患者的主要治疗方法,包括内放疗、三维适形放疗、三维调强放疗(IMRT)、立体定向放疗及放疗联合肝动脉化疗栓塞(TACE)等.对于微小病灶、外照射后残存或复发的病灶,内放疗可有目的性地放置放射性核素以提高靶器官辐射量,减少正常组织的辐射量.对于肿瘤边界不清,有癌栓、淋巴结转移或局部复发的患者,三维适形放疗、IMRT及放疗联合TACE则可以更好地使高剂量分布形状与靶区形状在三维空间上一致,提高局部控制率.
방료시무수술지정간세포간암(HCC)환자적주요치료방법,포괄내방료、삼유괄형방료、삼유조강방료(IMRT)、입체정향방료급방료연합간동맥화료전새(TACE)등.대우미소병조、외조사후잔존혹복발적병조,내방료가유목적성지방치방사성핵소이제고파기관복사량,감소정상조직적복사량.대우종류변계불청,유암전、림파결전이혹국부복발적환자,삼유괄형방료、IMRT급방료연합TACE칙가이경호지사고제량분포형상여파구형상재삼유공간상일치,제고국부공제솔.
Radiation therapy is a primary treatment for the unresectable hepatocellular carcinoma (HCC),including internal radiotherapy,three-dimensional conformal radiotherapy,three-dimensional intensity modulated radiotherapy (IMRT),stereotactic radiotherapy and radiotherapy combined with transcatheter arterial chemoembolization (TACE).For small lesions,residual or recurrent lesions after external irradiation,the internal radiotherapy can purposefully place radionuclides to increase the amount of radiation in target organs and reduce the amount of radiation in normal tissue.For the patients with unclear tumor boundary,thrombosis,lymph node metastasis or local recurrence,three-dimensional conformal radiotherapy,IMRT and radiotherapy combined with TACE can better make the target high-dose distribution shape fit with three-dimensional space accurately,and improve the local control rate.