CAJ | 학술논문

甲状腺癌的发病与多种因素有关,辐射是明确的危险因素,碘摄取量与甲状腺癌的关系仍存在争议.研究表明,多个信号传导通路中遗传学和表观遗传学的改变是甲状腺癌分子致病机制的核心.另外,促甲状腺素、体重指数和慢性淋巴细胞性甲状腺炎也与甲状腺癌的发生有关.
갑상선암적발병여다충인소유관,복사시명학적위험인소,전섭취량여갑상선암적관계잉존재쟁의.연구표명,다개신호전도통로중유전학화표관유전학적개변시갑상선암분자치병궤제적핵심.령외,촉갑상선소、체중지수화만성림파세포성갑상선염야여갑상선암적발생유관.
The incidence of thyroid carcinoma is associated with a variety of factors.Radiation is the clear risk factor,the relationship between iodine intake and thyroid carcinoma remains controversial.Researches show that the genetic and epigenetic changes of many signaling pathways are the key of molecular pathogenetic mechanism of thyroid carcinoma.In addition,thyroid stimulating hormone,body mass index and chronic lymphocytic thyroiditis are also associated with thyroid carcinoma.