CAJ | 학술논문

微小RNA (miRNA)在细胞生长、分化、凋亡和肿瘤发生中发挥重要的调控作用.研究显示,miRNA调控目的基因表达与结直肠癌的发生发展、化疗敏感性及预后密切相关.检测miRNA有望为结直肠癌患者制定更详细的个体化化疗方案,并改善其预后.
미소RNA (miRNA)재세포생장、분화、조망화종류발생중발휘중요적조공작용.연구현시,miRNA조공목적기인표체여결직장암적발생발전、화료민감성급예후밀절상관.검측miRNA유망위결직장암환자제정경상세적개체화화료방안,병개선기예후.
MicroRNAs (miRNAs) are involved in cell growth,differentiation,apoptosis and tumor occurrence and play an important role in regulation.Many studies show that miRNAs can regulate the expression of target gene,which is associated closely with the occurrence,development,chemosensitivity and prognosis of colorectal cancer.Detection of miRNAs is expected to formulate more detailed individualized chemotherapy for colorectal cancer patients and improve their prognosis.