CAJ | 학술논문

鼻咽癌的发病原因至今尚不十分清楚,最新的证据表明表观遗传学参与了鼻咽癌的发生发展.表观遗传学改变可以作为鼻咽癌的分子指标,有利于判断预后.针对表观遗传学改变采取干预措施未来可作为新的鼻咽癌治疗手段,并且可以开发新的鼻咽癌放疗增敏剂和新的治疗药物.研究表观遗传学在鼻咽癌中的改变,为鼻咽癌的诊断、治疗等提供了新的思路.
비인암적발병원인지금상불십분청초,최신적증거표명표관유전학삼여료비인암적발생발전.표관유전학개변가이작위비인암적분자지표,유리우판단예후.침대표관유전학개변채취간예조시미래가작위신적비인암치료수단,병차가이개발신적비인암방료증민제화신적치료약물.연구표관유전학재비인암중적개변,위비인암적진단、치료등제공료신적사로.
The etiology of nasopharyngeal carcinoma is still not very clear.Epigenetics is proved to play an important role in the occurrence and development of nasopharyngeal carcinoma (NPC).Detection of epigenetics can serve as molecular index of NPC,and it is advantageous to the prognosis and disease of NPC.Different intervention measures in the epigenetics can be used as a new treatment of NPC,as well as the development of new NPC radiotherapy sensitization agent and new drugs.Study of epigenetics changes in nasopharyngeal carcinoma provides a new idea for the diagnosis and treatment in NPC and so on.