CAJ | 학술논문

微小RNA(miRNA)是一类小分子非编码RNA,通过与目标mRNA互补序列结合,在转录水平调控基因的表达.研究发现,包括弥漫大B细胞淋巴瘤在内的不同恶性肿瘤中存在特定的miRNA表达谱.因此,体液、组织标本中miRNA的表达将有望成为评估弥漫大B细胞淋巴瘤的新指标.
미소RNA(miRNA)시일류소분자비편마RNA,통과여목표mRNA호보서렬결합,재전록수평조공기인적표체.연구발현,포괄미만대B세포림파류재내적불동악성종류중존재특정적miRNA표체보.인차,체액、조직표본중miRNA적표체장유망성위평고미만대B세포림파류적신지표.
MicroRNA (miRNA) is a kind of naturally occurring short non-coding small molecular RNA,which regulates gene expression at the posttranscriptional level through its sequence complementation with target mRNAs.Researches have shown that different malignant tumors,including diffuse large B cell lymphoma,have specific miRNA expression profiles.Therefore,miRNAs expression level of specimens of body fluids and tissues is expected to be the new indicator for assessing diffuse large B cell lymphoma.