国际中医中药杂志
國際中醫中藥雜誌
국제중의중약잡지
INTERNATIONAL JOURNAL OF TRIDITIONAL CHINESE MEDICINE
2013年
4期
303-305
,共3页
龟龙饮%针刺%抑郁症%汉密尔顿抑郁量表%抑郁自评量表%5-羟色胺
龜龍飲%針刺%抑鬱癥%漢密爾頓抑鬱量錶%抑鬱自評量錶%5-羥色胺
구룡음%침자%억욱증%한밀이돈억욱량표%억욱자평량표%5-간색알
Turtle-Dragon decoction%acupuncture%depression%HAMD%SDS%5-HT
目的 观察龟龙饮联合针刺对抑郁症患者血浆5-羟色胺(5-HT)水平的影响.方法 按就诊顺序将70例患者随机分成两组各35例,治疗组采用龟龙饮联合针刺治疗,对照组采用盐酸氟西汀治疗.所有患者于治疗前、治疗后第8周检测血浆5-HT水平,并进行抑郁自评量表(SDS)和汉密尔顿抑郁量表(HAMD)评分.结果 两组患者治疗8周后,治疗组总有效率为80％、对照组为85.71％,两组比较差异无统计学意义(x2=o.40,P＞0.05),两组患者治疗后HAMD、SDS评分[治疗组分别为(9.31±2.10)分、(55.91±4.13)分,对照组分别为(9.36±2.28)分、(56.70±3.77)分]均较同组治疗前[治疗组分别为(12.79±2.50)分、(61.54±3.26)分,对照组分别为(11.89±2.73)分、(62.09±3.24)分]明显降低(P＜0.01);治疗后血浆5-HT水平[治疗组为(118.62±29.74) ng/ml,对照组为(121.10±30.56) ng/ml]均较同组治疗前[治疗组为(65.97±23.35) ng/ml,对照组为(63.40±21.24) ng/ml]显著提高(P＜0.01),但两组治疗后HAMD、SDS评分,血浆5-HT水平,组间比较差异无统计学意义(P＞0.05).结论 龟龙饮联合针刺可改善抑郁症患者HAMD、SDS评分,血浆5-HT含量得到提高,疗效与氟西汀相当.
目的 觀察龜龍飲聯閤針刺對抑鬱癥患者血漿5-羥色胺(5-HT)水平的影響.方法 按就診順序將70例患者隨機分成兩組各35例,治療組採用龜龍飲聯閤針刺治療,對照組採用鹽痠氟西汀治療.所有患者于治療前、治療後第8週檢測血漿5-HT水平,併進行抑鬱自評量錶(SDS)和漢密爾頓抑鬱量錶(HAMD)評分.結果 兩組患者治療8週後,治療組總有效率為80％、對照組為85.71％,兩組比較差異無統計學意義(x2=o.40,P＞0.05),兩組患者治療後HAMD、SDS評分[治療組分彆為(9.31±2.10)分、(55.91±4.13)分,對照組分彆為(9.36±2.28)分、(56.70±3.77)分]均較同組治療前[治療組分彆為(12.79±2.50)分、(61.54±3.26)分,對照組分彆為(11.89±2.73)分、(62.09±3.24)分]明顯降低(P＜0.01);治療後血漿5-HT水平[治療組為(118.62±29.74) ng/ml,對照組為(121.10±30.56) ng/ml]均較同組治療前[治療組為(65.97±23.35) ng/ml,對照組為(63.40±21.24) ng/ml]顯著提高(P＜0.01),但兩組治療後HAMD、SDS評分,血漿5-HT水平,組間比較差異無統計學意義(P＞0.05).結論 龜龍飲聯閤針刺可改善抑鬱癥患者HAMD、SDS評分,血漿5-HT含量得到提高,療效與氟西汀相噹.
목적 관찰구룡음연합침자대억욱증환자혈장5-간색알(5-HT)수평적영향.방법 안취진순서장70례환자수궤분성량조각35례,치료조채용구룡음연합침자치료,대조조채용염산불서정치료.소유환자우치료전、치료후제8주검측혈장5-HT수평,병진행억욱자평량표(SDS)화한밀이돈억욱량표(HAMD)평분.결과 량조환자치료8주후,치료조총유효솔위80％、대조조위85.71％,량조비교차이무통계학의의(x2=o.40,P＞0.05),량조환자치료후HAMD、SDS평분[치료조분별위(9.31±2.10)분、(55.91±4.13)분,대조조분별위(9.36±2.28)분、(56.70±3.77)분]균교동조치료전[치료조분별위(12.79±2.50)분、(61.54±3.26)분,대조조분별위(11.89±2.73)분、(62.09±3.24)분]명현강저(P＜0.01);치료후혈장5-HT수평[치료조위(118.62±29.74) ng/ml,대조조위(121.10±30.56) ng/ml]균교동조치료전[치료조위(65.97±23.35) ng/ml,대조조위(63.40±21.24) ng/ml]현저제고(P＜0.01),단량조치료후HAMD、SDS평분,혈장5-HT수평,조간비교차이무통계학의의(P＞0.05).결론 구룡음연합침자가개선억욱증환자HAMD、SDS평분,혈장5-HT함량득도제고,료효여불서정상당.
Objective To observe HAMD,SDS scores and plasma 5-tT content with Depressive Patients treated by Turtle-Dragon decoction combined with acupuncture.Methods 70 patients were randomly divided into the treatment group and the control group,the treatment group treated with the turtle dragon decoction combined with acupuncture,the control group treated with fluoxetine hydrochloride,all patients before treatment and after treated 8 weeks were measured by HAMD,SDS and detected by plasma 5-HT content.Results Two groups of patients after 8 weeks of treatment,the total effective rate was 80％ in the treatment group,the total effective rate was 85.71％ in the control group,two groups showed no significant difference (x2=0.40,P＞0.05).HAMD and SDS[the treatment group were(9.31 ± 2.10) points,(55.91± 4.13) points,the control group were(9.36±2.28)points,(56.70±3.77)points] scores were significantly lower(P＜0.01) than before treatment[the treatment group were(12.79±2.50)points,(61.54±3.26)points,the control group were(11.89±2.73)points,(62.09±3.24)points] in all the patients,Plasma 5-HT content[the treatment group were (118.62 ± 29.74) ng/ml,the control group were (121.10 ± 30.56) ng/ml] has been significantly improved (P＜0.01) after treatment[the treatment group were(65.97±23.35)ng/ml,the control group were(63.40±21.24) ng/ml] in all the patients.Between the two groups of patients after treatment,the comparison of the HAMD,SDS scores and Plasma 5-HT content was no significant difference (P ＞ 0.05).Conclusion Turtle-Dragon decoction combined with acupuncture can obviously improve the HAMD,SDS scores and plasma 5-HT content with Depressive Patients.Also treatments between two groups have equivalent effects.
