CAJ | 학술논문

目的探讨彩超监测中药“肝复安”对乙型肝炎相关性肝癌高危状态干预过程中的辅助作用.方法以多项肿瘤标志物联合检测为依据,在慢性乙型肝炎患者中筛选出85例肝癌高危者患者用中药“肝复安”方进行干预治疗.50例作为治疗组,以彩超和肿瘤标志物联合监测,随症调整治疗；35例作为对照组常规治疗.结果治疗组经密切监测治疗后,肝癌肿瘤标志物持续转阴或部分肝内肿瘤消失.肿瘤阻断型5例、干预有效型38例、干预失效型7例,累计肝癌发生率为14％ (7/50)；对照组中肿瘤阻断型0例、干预有效型20例、干预失效型15例,累计慢性肝炎是导致肝细胞性肝癌(hepatocellular carcinoma,HCC)发生率为43％ (15/35),均经病理确诊.结论彩超可直观无创动态监测肝脏肿瘤的消长情况.
목적 탐토채초감측중약“간복안”대을형간염상관성간암고위상태간예과정중적보조작용.방법 이다항종류표지물연합검측위의거,재만성을형간염환자중사선출85례간암고위자환자용중약“간복안”방진행간예치료.50례작위치료조,이채초화종류표지물연합감측,수증조정치료；35례작위대조조상규치료.결과 치료조경밀절감측치료후,간암종류표지물지속전음혹부분간내종류소실.종류조단형5례、간예유효형38례、간예실효형7례,루계간암발생솔위14％ (7/50)；대조조중종류조단형0례、간예유효형20례、간예실효형15례,루계만성간염시도치간세포성간암(hepatocellular carcinoma,HCC)발생솔위43％ (15/35),균경병리학진.결론 채초가직관무창동태감측간장종류적소장정황.
Objective To study the supporting role of traditional Chinese medicine GanFuAn in the treatment of high-risk state of liver cancer by color Doppler ultrasound.Methods Based on a number of joint detection of tumor markers,85 patients of liver cancer were selected from patients with chronic hepatitis B.Among these 85patients,50 patients were selected in a treatment group and treated with Chinese herbal preparation GanFuAn,with ultrasound and tumor markers serving as joint monitoring; while the other 35 patients were selected in a control group and treated with conventional treatment.Results In the treatment group,the liver tumor markers or liver tumor continually diminished.5 cases showed tumor disappear.38 cases showed effective results,while 7 cases showed no effects.The total incidence rate of liver cancer was 14％;while in the control group,none case showed tumor disappear.20 cases showed effects and 15 cases showed none effects.The cumulative incidence rate of liver cancer induced by chronic hepatitis was 43％,with all the cases have been confirmed by pathology.Conclusion Color doppler ultrasound was an intuitive,non-invasive dynamic method to monitor liver tumor's growth and decline.