CAJ | 학술논문

目的探讨乳腺导管内癌(DCIS)行前哨淋巴结活检术(SLNB)的临床意义.方法回顾性分析2002年1月至2007年6月行SLNB的86例乳腺DCIS及51例导管内癌微浸润(DCISM)临床资料,分析影响其前哨淋巴结(SLN)阳性率的凶素.结果 86例DCIS中,行保乳手术42例,乳房切除术44例,3例(3.5%)因SLN阳性改行腋清扫术,并均为唯一转移的腋淋巴结.51例DCISM中,行保乳手术13例,乳房切除术38例,4例(7.8%)SLN阳性,1例存在腋窝非前哨淋巴结转移.所有患者中位随访4年,均未见同侧腋窝复发及远处转移.结论 DCISM应该常规行SLNB;行乳房切除手术的DCIS应同时行SLNB,行保乳手术者可不行SLNB.
목적 탐토유선도관내암(DCIS)행전초림파결활검술(SLNB)적림상의의.방법 회고성분석2002년1월지2007년6월행SLNB적86례유선DCIS급51례도관내암미침윤(DCISM)림상자료,분석영향기전초림파결(SLN)양성솔적흉소.결과 86례DCIS중,행보유수술42례,유방절제술44례,3례(3.5%)인SLN양성개행액청소술,병균위유일전이적액림파결.51례DCISM중,행보유수술13례,유방절제술38례,4례(7.8%)SLN양성,1례존재액와비전초림파결전이.소유환자중위수방4년,균미견동측액와복발급원처전이.결론 DCISM응해상규행SLNB;행유방절제수술적DCIS응동시행SLNB,행보유수술자가불행SLNB.
Objective To evaluate the roles of sentinel lymph node biopsy (SLNB) for patients with breast ductal carcinoma in situ (DCIS). Methods A database containing 86 breast DCIS patients and 51 ductal carcinoma in situ with microinvasion (DCISM) patients who received SLNB from Jan. 2002 to Jun. 2007 was retrospectively analyzed. Results Of the 86 DCIS patients, 42 received breast conserving surgery and 44 received mastectomy. Three patients (3.5%) had sentinel lymph node (SLN) metastasis, and the SLN is the only lymph node with metastasis. Of 51 DCISM patients, 13 received breast conserving surgery and 38 received mastectomy. 4 patients (7.8%) had SLN metastasis and 1 had non sentinel lymph nodes metastasis. After a median follow-up of four years, none of the patients had ipsilateral axillary recurrence and further metastasis. Conclusions SLNB should be done in all DCISM patients and those DCIS patients who received mastectomy, and be avoided in those who received breast conserving surgery.