中华内分泌外科杂志
中華內分泌外科雜誌
중화내분비외과잡지
CHINESE JOURNAL OF ENDOCRINE SURGERY
2012年
6期
384-387
,共4页
糖尿病溃疡创面%细菌培养%药敏试验
糖尿病潰瘍創麵%細菌培養%藥敏試驗
당뇨병궤양창면%세균배양%약민시험
Diabetic ulcer%Bacterial culture%Drug sensitivity test
目的 探讨糖尿病溃疡创面细菌学特点及药敏结果.方法 前瞻性收集重庆医科大学附属第一医院整形烧伤科2010年3月至2011年9月收治的130例糖尿病溃疡创面分泌物作细菌培养,用常用抗生素35种中的28种做出抗生素敏感(S)、中敏(I)、耐药(R)的判断并分析.结果 130例糖尿病溃疡创面分泌物培养出19种细菌,前6位分别是金黄色葡萄球菌14.62％ (19/130),大肠埃希菌13.85％(18/130),奇异变形杆菌13.08％ (17/130),表皮葡萄球菌12.31％ (16/130),粪肠球菌12.31％(16/130),鲍曼不动杆菌10.77％(14/130).革兰阳性菌敏感率较高的抗生素为替加环素、万古霉素,革兰阴性菌敏感率较高的抗生素为亚胺培南、丁胺卡那.结论 糖尿病溃疡创面细菌对常用抗生素耐药较普遍.了解常见病原菌分布及其耐药性对临床合理用药具有重要意义.
目的 探討糖尿病潰瘍創麵細菌學特點及藥敏結果.方法 前瞻性收集重慶醫科大學附屬第一醫院整形燒傷科2010年3月至2011年9月收治的130例糖尿病潰瘍創麵分泌物作細菌培養,用常用抗生素35種中的28種做齣抗生素敏感(S)、中敏(I)、耐藥(R)的判斷併分析.結果 130例糖尿病潰瘍創麵分泌物培養齣19種細菌,前6位分彆是金黃色葡萄毬菌14.62％ (19/130),大腸埃希菌13.85％(18/130),奇異變形桿菌13.08％ (17/130),錶皮葡萄毬菌12.31％ (16/130),糞腸毬菌12.31％(16/130),鮑曼不動桿菌10.77％(14/130).革蘭暘性菌敏感率較高的抗生素為替加環素、萬古黴素,革蘭陰性菌敏感率較高的抗生素為亞胺培南、丁胺卡那.結論 糖尿病潰瘍創麵細菌對常用抗生素耐藥較普遍.瞭解常見病原菌分佈及其耐藥性對臨床閤理用藥具有重要意義.
목적 탐토당뇨병궤양창면세균학특점급약민결과.방법 전첨성수집중경의과대학부속제일의원정형소상과2010년3월지2011년9월수치적130례당뇨병궤양창면분비물작세균배양,용상용항생소35충중적28충주출항생소민감(S)、중민(I)、내약(R)적판단병분석.결과 130례당뇨병궤양창면분비물배양출19충세균,전6위분별시금황색포도구균14.62％ (19/130),대장애희균13.85％(18/130),기이변형간균13.08％ (17/130),표피포도구균12.31％ (16/130),분장구균12.31％(16/130),포만불동간균10.77％(14/130).혁란양성균민감솔교고적항생소위체가배소、만고매소,혁란음성균민감솔교고적항생소위아알배남、정알잡나.결론 당뇨병궤양창면세균대상용항생소내약교보편.료해상견병원균분포급기내약성대림상합리용약구유중요의의.
Objective To evaluate the features of bacterial spectrum and drug resistance in diabetic ulcer.Methods Excretion specimen of diabetic ulcer from 130 patients admitted into our hospital from Mar.2010 to Sep.2011 were collected for bacterial culture and drug sensitivity test.28 antibiotics were chosen from 35commonly used antibiotics to test antibiotic sensitivity to decide whether the antibiotic was sensitive (S),intermediate sensitive (I),or resistant (R).Results 19 strains were isolated from 130 cases.Staphylococcus aureus with 14.62 ％ (19 cases)rated the first,followed by escherichia coli with 13.85％ (18 cases),proteus mirabilis with 13.08％ (17 cases),staphylococcus epidermidis with 12.31％ (16 cases),enterococcus faecalis with 12.31％ (16 cases),acinetobacter baumannii with 10.77％ (14 cases).Antibiotics with high sensitivity to Gram-positive bacteria were tigecycline and vancomycin while with high sensitivity to Gram-negative bacteria were imipenem and amikacin.Conclusions Bacteria of diabetic ulcer are commonly resistant to antibiotics.It is of great importance for clinical rational drug use to know the distribution and resistance of commonly encountered bacteria.
