中华内分泌外科杂志
中華內分泌外科雜誌
중화내분비외과잡지
CHINESE JOURNAL OF ENDOCRINE SURGERY
2014年
3期
223-226
,共4页
李宇%滕长胜%屈翔%赵宁%葛智成%张慧明%苑著%张忠涛
李宇%滕長勝%屈翔%趙寧%葛智成%張慧明%苑著%張忠濤
리우%등장성%굴상%조저%갈지성%장혜명%원저%장충도
甲状腺乳头状癌%中央区淋巴结%侧区淋巴结%转移
甲狀腺乳頭狀癌%中央區淋巴結%側區淋巴結%轉移
갑상선유두상암%중앙구림파결%측구림파결%전이
Papillary thyroid cancer%Central cervical lymph node%Lateral cervical lymph node%Metastasis
目的 探讨甲状腺乳头状癌中央区淋巴结阳性与侧区淋巴结的关系.方法 回顾性分析首都医科大学附属北京友谊医院2009年1月至2012年12月行预防性颈淋巴结清扫的50例甲状腺乳头状癌资料.女36例,男14例.结果 根据患者中央区淋巴结阳性数目分为3组:中央区淋巴结转移数=1(A组,n =21),中央区淋巴结转移数=2(B组,n=11),中央区淋巴结转移数≥3(C组,n=18),各组相应侧区淋巴结受累的风险分别为47.5％、81.8％、88.9％ (P =0.012).单因素分析提示T3～4及中央区淋巴结阳性数≥2枚是侧区淋巴结转移的危险因素.多因素分析提示中央区淋巴结阳性数≥2枚是独立的危险因素(OR 4.67,95％ CI1 ～22),阳性预测值为86.2％.结论 T3～4或中央区淋巴结阳性数量≥2枚是PTC侧区淋巴结转移的高危因素,可考虑行预防性颈部淋巴结清扫.
目的 探討甲狀腺乳頭狀癌中央區淋巴結暘性與側區淋巴結的關繫.方法 迴顧性分析首都醫科大學附屬北京友誼醫院2009年1月至2012年12月行預防性頸淋巴結清掃的50例甲狀腺乳頭狀癌資料.女36例,男14例.結果 根據患者中央區淋巴結暘性數目分為3組:中央區淋巴結轉移數=1(A組,n =21),中央區淋巴結轉移數=2(B組,n=11),中央區淋巴結轉移數≥3(C組,n=18),各組相應側區淋巴結受纍的風險分彆為47.5％、81.8％、88.9％ (P =0.012).單因素分析提示T3～4及中央區淋巴結暘性數≥2枚是側區淋巴結轉移的危險因素.多因素分析提示中央區淋巴結暘性數≥2枚是獨立的危險因素(OR 4.67,95％ CI1 ～22),暘性預測值為86.2％.結論 T3～4或中央區淋巴結暘性數量≥2枚是PTC側區淋巴結轉移的高危因素,可攷慮行預防性頸部淋巴結清掃.
목적 탐토갑상선유두상암중앙구림파결양성여측구림파결적관계.방법 회고성분석수도의과대학부속북경우의의원2009년1월지2012년12월행예방성경림파결청소적50례갑상선유두상암자료.녀36례,남14례.결과 근거환자중앙구림파결양성수목분위3조:중앙구림파결전이수=1(A조,n =21),중앙구림파결전이수=2(B조,n=11),중앙구림파결전이수≥3(C조,n=18),각조상응측구림파결수루적풍험분별위47.5％、81.8％、88.9％ (P =0.012).단인소분석제시T3～4급중앙구림파결양성수≥2매시측구림파결전이적위험인소.다인소분석제시중앙구림파결양성수≥2매시독립적위험인소(OR 4.67,95％ CI1 ～22),양성예측치위86.2％.결론 T3～4혹중앙구림파결양성수량≥2매시PTC측구림파결전이적고위인소,가고필행예방성경부림파결청소.
Objective To analyze the relationship between central cervical lymph node metastasis and the lateral cervical lymph node metastasis in cN0 papillary thyroid cancer.Methods We retrogradely analyze 50 cases of papillary thyroid cancer who had prophylactic modified neck dissection in recent three years.There were 36 females and 14 males patients.Patients were divided into three groups according to the number of positive CCLN:groupA=1(n=21); B=2(n=11) andC≥3(n=18).Results The risk of lateral compartment lymph nodes involvement increased in parallel with the number of positive CCLN(47.5％ vs.81.8％ vs.88.9％ in groups A,B and C,respectively; P =0.012).Univariate analysis revealed the number of CCLN ≥ 2 (P =0.04),T3-4 (P =0.049) were risk factors for the metastasis in the lateral neck.However,multi-variate analysis implied only the C CLN ≥ 2 was the independent factor(OR 4.67,95 ％ CI 1 ～22),with a positive predictive value 86.2％.Conclusion T3-4 and positive CCLN ≥ 2 are risk factors for lateral compartment involvement in cN0 PTC,prophylactic modified neck dissection can be considered.
