CAJ | 학술논문

目的验证EORTC QLQ-LC43量表在中国肺癌患者中应用的有效性.方法以2012年11月至2013年4月在天津肿瘤医院接受门诊治疗的214例肺癌患者作为调查对象,同时完成量表EORTC QLQ-LC43和SF-36的测评,并进行KPS评分,对结果采用Cronbach α系数、Pearson 相关检验及Kruskal-Wallis检验进行统计分析.结果除认知功能(Cronbach α=0.401)外,其余各维度信度均较好(Cronbach α＞0.7);EORTC QLQ-LC43与SF-36中相同或相似的维度具有较好的相关性,共性量表C30中与功能相关的维度除情绪功能(EF)外,各维度与KPS得分相关性均较好,而与症状相关的维度相关性则较低,在肺癌症状子量表中,呼吸困难(LC-DY)与KPS的相关性较好,其余条目均相关性一般;按照KPS评分高低将患者分为3组,组间LC43评分比较,除DY、LC-HA维度外,差异均有统计学意义.结论 EORTC QLQ-LC43量表应用于中国肺癌患者,具有良好的信度和效度.
목적 험증EORTC QLQ-LC43량표재중국폐암환자중응용적유효성.방법 이2012년11월지2013년4월재천진종류의원접수문진치료적214례폐암환자작위조사대상,동시완성량표EORTC QLQ-LC43화SF-36적측평,병진행KPS평분,대결과채용Cronbach α계수、Pearson 상관검험급Kruskal-Wallis검험진행통계분석.결과 제인지공능(Cronbach α=0.401)외,기여각유도신도균교호(Cronbach α＞0.7);EORTC QLQ-LC43여SF-36중상동혹상사적유도구유교호적상관성,공성량표C30중여공능상관적유도제정서공능(EF)외,각유도여KPS득분상관성균교호,이여증상상관적유도상관성칙교저,재폐암증상자량표중,호흡곤난(LC-DY)여KPS적상관성교호,기여조목균상관성일반;안조KPS평분고저장환자분위3조,조간LC43평분비교,제DY、LC-HA유도외,차이균유통계학의의.결론 EORTC QLQ-LC43량표응용우중국폐암환자,구유량호적신도화효도.
Objective This study investigated the validity and reliability of the standard Chinese version of EORTC QLQ-LC43 in patients with lung cancer in China.Methods EORTC QLQ-LC43 and SF-36 was administered to community-based sample of 214 out-patients with lung cancer in Tianjin Medical University Cancer Institute and Hospital,and Karnofsky Performance Status (KPS) was applied as a clinical variable.Reliability and validity were assessed using internal consistency,Pearson correlation coefficient and Kruskal-Wallis test.Results Internal consistency reliability (Cronbach alpha ＞0.70) of the subscales were acceptable except for the cognitive functioning scale (Cronbach alpha =0.401).The correlation coefficients between similar dimensions of the EORTC QLQ-C43 and the SF-36 questionnaires ranged from 0.407 to 0.664.And that between the functional scales of the EORTC QLQ-C43 and KPS were all above 0.40 excluding emotional functioning scale.The correlation coefficients between the symptom scales of the EORTC QLQ-C43 and KPS were low except for LC-DY.When the data were divided into three groups according to the scores of the KPS the worst to the best,it showed that when the KPS values increased,the functioning scale scores increased and the symptom scale scores decreased.The mean scores in the three groups were different from each other.Conclusions The Chinese version of the EORTC QLQ-LC43 showed good reliability and validity.The scale is appropriate for use in patients with lung cancer in China.