中国实用护理杂志
中國實用護理雜誌
중국실용호리잡지
CHINESE JOURNAL OF PRACTICAL NURSING
2013年
35期
1-6
,共6页
刘晶晶%章新琼%洪静芳%宋永霞
劉晶晶%章新瓊%洪靜芳%宋永霞
류정정%장신경%홍정방%송영하
胃癌%肠内营养%早期%Meta分析
胃癌%腸內營養%早期%Meta分析
위암%장내영양%조기%Meta분석
Gastric cancer%Enteral nutrition%Early period%Meta-analysis
目的 采用循证医学方法对国内胃癌术后早期肠内营养支持文献进行系统评价,为临床营养干预提供循证依据.方法 计算机检索中国生物医学文献数据库、中国学术期刊、万方数据库以及维普信息资源系统中2000年1月至2013年3月的文献,按照纳入和排除标准收集国内发表的胃癌术后早期肠内营养和肠外营养比较的临床随机对照实验类文献,采用Cochrane系统评价员手册以独立、双盲的原则对纳入文献进行方法学质量评价,最后数据应用RevMan5.2软件进行Meta分析.结果 纳入的14篇研究中,Meta分析表明:胃癌术后早期肠内营养与肠外营养相比,术后血清白蛋白的加权均数差为1.55,95％CI (0.81,2.29);患者术后血清转铁蛋白的加权均数差为0.34,95％CI(0.30,0.38);术后肛门排气时间的加权均数差为-20.66,95％CI(-23.91,-17.40).结论 胃癌患者术后早期肠内营养支持效果优于肠外营养,可以提供患者术后恢复足够的血清蛋白原,并能较早恢复胃肠道消化吸收功能,值得临床推广.
目的 採用循證醫學方法對國內胃癌術後早期腸內營養支持文獻進行繫統評價,為臨床營養榦預提供循證依據.方法 計算機檢索中國生物醫學文獻數據庫、中國學術期刊、萬方數據庫以及維普信息資源繫統中2000年1月至2013年3月的文獻,按照納入和排除標準收集國內髮錶的胃癌術後早期腸內營養和腸外營養比較的臨床隨機對照實驗類文獻,採用Cochrane繫統評價員手冊以獨立、雙盲的原則對納入文獻進行方法學質量評價,最後數據應用RevMan5.2軟件進行Meta分析.結果 納入的14篇研究中,Meta分析錶明:胃癌術後早期腸內營養與腸外營養相比,術後血清白蛋白的加權均數差為1.55,95％CI (0.81,2.29);患者術後血清轉鐵蛋白的加權均數差為0.34,95％CI(0.30,0.38);術後肛門排氣時間的加權均數差為-20.66,95％CI(-23.91,-17.40).結論 胃癌患者術後早期腸內營養支持效果優于腸外營養,可以提供患者術後恢複足夠的血清蛋白原,併能較早恢複胃腸道消化吸收功能,值得臨床推廣.
목적 채용순증의학방법대국내위암술후조기장내영양지지문헌진행계통평개,위림상영양간예제공순증의거.방법 계산궤검색중국생물의학문헌수거고、중국학술기간、만방수거고이급유보신식자원계통중2000년1월지2013년3월적문헌,안조납입화배제표준수집국내발표적위암술후조기장내영양화장외영양비교적림상수궤대조실험류문헌,채용Cochrane계통평개원수책이독립、쌍맹적원칙대납입문헌진행방법학질량평개,최후수거응용RevMan5.2연건진행Meta분석.결과 납입적14편연구중,Meta분석표명:위암술후조기장내영양여장외영양상비,술후혈청백단백적가권균수차위1.55,95％CI (0.81,2.29);환자술후혈청전철단백적가권균수차위0.34,95％CI(0.30,0.38);술후항문배기시간적가권균수차위-20.66,95％CI(-23.91,-17.40).결론 위암환자술후조기장내영양지지효과우우장외영양,가이제공환자술후회복족구적혈청단백원,병능교조회복위장도소화흡수공능,치득림상추엄.
Objective In order to evaluate the nutritional effect of early enteral nutrition in patients of Chinese domestic gastric cancer surgery,using evidence-based medicine methods,and supply evidence for clinical nutrition intervention.Methods CBM,Chinese academic Journals,Wanfang database and VIP Information Resource System were searched from January 2000 to March 2013 to collect the published clinical randomized controlled trials literatures of nutrition support in patients of Chinese domestic gastric cancer surgery according to inclusion and exclusion criteria of literature,using the Cochrane System Evaluation Handbook independent,double-blind principle of the literature methodology quality evaluation.Finally Meta analysis was conducted by using RevMan5.2 software.Results 14 articles were enrolled in the study,Meta analysis results showed that:early enteral nutrition comparing with parenteral nutrition in postoperative gastric cancer patients:the WMD of serum albumin was 1.55,95％ CI (0.81,2.29); the WMD of serum transferrin was 0.34,95％CI (0.30,0.38);the WMD of postoperative anal exhaust time was-20.66,95％CI (-23.91,-17.40).Conclusions Early enteral nutrition is better than the parenteral nutrition,which can restore adequate serum protein source for patients,and can recover the gastrointestinal digestion and absorption function of itself earlier,which is worthy of clinical promotion.
