CAJ | 학술논문

目的评价中文烧心版本反流和消化不良生活质量量表(QOLRAD)的信度、效度和反应度.方法采用中文烧心版本QOLRAD和汉化版简明健康调查问卷SF-36,对门诊130例胃食管反流病患者进行问卷调查,同时纳入接受质子泵抑制剂治疗8周的胃食管反流病患者30例,比较其治疗前后变化进行反应度评价.结果 (1)信度:该量表总的Cronbach α系数为0.89,各维度Cronbach α系数为0.70～0.90.(2)效度:该量表适合患者理解和填写,代表性好,专家评定内容效度指数(CVI)值为0.82.探索性因子分析提取5个公因子,5个公因子对方差的累积贡献率为62.02％,大多数条目在所属维度均有较大负荷(＞0.4).中文版QOLRAD除饮食问题与SF-36个别维度(社会功能、身体疼痛和精神健康)无相关性,两量表其余各维度之间相关系数为0.172～0.613,差异有统计学意义.(3)反应度:经8周质子泵抑制剂治疗后,除睡眠障碍外,活力、生理/社会功能、饮食问题和情绪不适4个维度较治疗前明显增高.结论中文烧心版本QOLRAD量表具有较好的信度、效度和反应度,可以用于胃食管反流病患者生活质量评价.
목적 평개중문소심판본반류화소화불량생활질량량표(QOLRAD)적신도、효도화반응도.방법 채용중문소심판본QOLRAD화한화판간명건강조사문권SF-36,대문진130례위식관반류병환자진행문권조사,동시납입접수질자빙억제제치료8주적위식관반류병환자30례,비교기치료전후변화진행반응도평개.결과 (1)신도:해량표총적Cronbach α계수위0.89,각유도Cronbach α계수위0.70～0.90.(2)효도:해량표괄합환자리해화전사,대표성호,전가평정내용효도지수(CVI)치위0.82.탐색성인자분석제취5개공인자,5개공인자대방차적루적공헌솔위62.02％,대다수조목재소속유도균유교대부하(＞0.4).중문판QOLRAD제음식문제여SF-36개별유도(사회공능、신체동통화정신건강)무상관성,량량표기여각유도지간상관계수위0.172～0.613,차이유통계학의의.(3)반응도:경8주질자빙억제제치료후,제수면장애외,활력、생리/사회공능、음식문제화정서불괄4개유도교치료전명현증고.결론 중문소심판본QOLRAD량표구유교호적신도、효도화반응도,가이용우위식관반류병환자생활질량평개.
Objective To assess the psychometric properties of the Chinese Heartburn Version of Quality of Life in Reflux and Dyspepsia Questionnaire (QOLRAD) in patients with gastroesophageal reflux disease.Methods 130 patients with symptoms of heartburn completed the Chinese version of QOLRAD,the Short-Form-36 (SF-36).30 of them received proton pump inhibitors (PPI) for 8 weeks,which was used to test responsiveness of the Chinese heartburn version of QOLRAD.Results The Chinese version of QOLRAD had acceptable internal consistency.The overall Cronbach's alpha was 0.89 and the internal consistency of dimensions ranged from 0.70～0.90.Content validity index (CVI) was 0.82.Confirmation factor analysis revealed a 5 factor solutions accounting for 62.02％ and most of items in their dimensions had acceptable loads (＞0.4).There was acceptable concurrent validity with correlations between the Chinese heartburn version of QOLRAD and Short Form-36 health survey ranging from 0.172～0.613.As to responsiveness,after therapy of PPI for 8 weeks,except the dimension of sleep disturbance,scores for dimensions of vitality,food/drink problems,physical/social functioning,emotional distress had significant changes.Conclusions The Chinese version of QOLRAD has a good reliability,validity and responsiveness to therapy,which can be used to assess the quality of life in patients with gastroesophageal reflux disease.