CAJ | 학술논문

目的评价持续声门下吸引对于机械通气危重患者呼吸机相关性肺炎发生的影响.方法计算机检索有关持续声门下吸引对比非声门下吸引降低呼吸机相关性肺炎发生率的随机对照试验,由2名研究者按照纳入和排除标准筛选文献,对文献质量进行严格评价并提取资料,对符合质量标准的研究使用Revman5.2软件进行Meta分析.结果 Meta分析结果表明,持续声门下吸引与非声门下吸引比较,可以减少呼吸机相关性肺炎的发生,缩短入住ICU时间,缩短机械通气时间.而对住院病死率的影响2组差异无统计学意义.结论持续声门下吸引可以降低机械通气危重患者呼吸机相关性肺炎发生率,缩短入住ICU时间以及机械通气时间.
목적 평개지속성문하흡인대우궤계통기위중환자호흡궤상관성폐염발생적영향.방법 계산궤검색유관지속성문하흡인대비비성문하흡인강저호흡궤상관성폐염발생솔적수궤대조시험,유2명연구자안조납입화배제표준사선문헌,대문헌질량진행엄격평개병제취자료,대부합질량표준적연구사용Revman5.2연건진행Meta분석.결과 Meta분석결과표명,지속성문하흡인여비성문하흡인비교,가이감소호흡궤상관성폐염적발생,축단입주ICU시간,축단궤계통기시간.이대주원병사솔적영향2조차이무통계학의의.결론 지속성문하흡인가이강저궤계통기위중환자호흡궤상관성폐염발생솔,축단입주ICU시간이급궤계통기시간.
Objective To assess the effectiveness of continuous aspiration of subglottic secretions (CASS)in preventing ventilator-associated pneumonia.Methods The relevant randomized controlled trials were searched in the Cochrane Library,Pubmed,CNKI,VIP and Wanfang databases.The experimental group received CASS and the control group did not(NASS group).Two reviewers selected studies according to the inclusion and exclusion criteria,the quality of studies was critically appraised and data were extracted by two reviewers independently.Meta-analysis was conducted by using RevMan 5.2.Results Sixteen randomized controlled trials met the inclusion criteria and enrolled 2 576 patients.According to the meta analysis,compared with NASS,CASS reduced the incidence of ventilator-associated pneumonia,shortened the length of stay in the intensive care unit and the duration of mechanical ventilation.There was no effect on hospital mortality.Conclusions Continuous aspiration of subglottic secretions appears effective in preventing ventilator-associated pneumonia,decreasing the duration of intensive care unit length of stay and mechanical ventilation among critically ill patients with mechanical ventilation.