CAJ | 학술논문

目的用Meta分析的方法比较水合氯醛口服和直肠内给药的镇静效果.方法收集比较水合氯醛口服和直肠内给药镇静效果的随机对照研究,采用RevMan5.0软件对纳入的10篇文献进行统计学分析.结果经分析直肠内给药有效率高于口服给药.口服给药患儿有95例出现胃肠道反应,直肠内给药有57例出现排便反应.结论水合氯醛直肠内给药的镇静效果优于口服给药.儿科应用水合氯醛镇静时特别注意用药安全,避免药物不良反应发生.
목적 용Meta분석적방법비교수합록철구복화직장내급약적진정효과.방법 수집비교수합록철구복화직장내급약진정효과적수궤대조연구,채용RevMan5.0연건대납입적10편문헌진행통계학분석.결과 경분석직장내급약유효솔고우구복급약.구복급약환인유95례출현위장도반응,직장내급약유57례출현배편반응.결론 수합록철직장내급약적진정효과우우구복급약.인과응용수합록철진정시특별주의용약안전,피면약물불량반응발생.
Objective To compare the sedative efficacy with oral or rectal chloral hydrate in pediatric patients by using Meta-analysis method.Methods Ten randomized controlled trials about the sedative efficacy with oral or rectal chloral hydrate in pediatric patients were retrieved.Meta-analysis was carried out using the RevMan 5.0 software.Results The results showed that the sedative efficacy with rectal medication was better than that with oral way.Nausea and vomiting occurred in 95 children with oral chloral hydrate,bowel movement occurred in 57 children with rectal chloral hydrate.Conclusions The sedative efficacy with rectal chloral hydrate was better than that with oral way.The safety in pediatric sedation with chloral hydrate should be emphasized in order to avoid adverse reaction.