中华现代护理杂志
中華現代護理雜誌
중화현대호리잡지
CHINESE JOURNAL OF MODERN NURSING
2012年
29期
3481-3484
,共4页
孙红娟%王玥妮%张凌%于新颖
孫紅娟%王玥妮%張凌%于新穎
손홍연%왕모니%장릉%우신영
乳腺肿瘤%新辅助化疗%癌因性疲乏%生活质量
乳腺腫瘤%新輔助化療%癌因性疲乏%生活質量
유선종류%신보조화료%암인성피핍%생활질량
Breast cancer%Neoadjuvant chemotherapy%Cancer related fatigue%Quality of life
目的 了解乳腺癌患者在接受新辅助化疗前后的癌因性疲乏及生活质量现状以及癌因性疲乏与生活质量的相关性,为临床护理干预提供依据.方法 采用方便取样法,对2009年11月至2010年5月北京某肿瘤医院乳腺中心化疗门诊接受新辅助化疗的115名乳腺癌患者,通过Piper疲乏修订量表和简明健康调查问卷进行调查.结果 新辅助化疗后患者在疲乏总分[2.4(0,9.0)]、行为[1.7(0,10.0)]、情感[1.8(0,8.4)]、感知[2.2(0,10.0)]、认知情绪[1.8(0,10.0)]四个维度得分均高于化疗前[0(0,8.9),0(0,8.5),0(0,10.0),0(0,9.4),0(0,9.3)],化疗前后比较,差异具有统计学意义(Z值分别为-5.874,-5.892,-5.668,-5.712,-5.363；P＜0.01)；患者的生话质量各维度(除精神健康外)得分与新辅助化疗前的得分比较差异均有统计学意义(P＜0.01)；化疗后疲乏与生活质量的精力、情感职能、生理职能、社会功能、精神健康、一般健康状况、生理机能等7个维度得分呈负相关,表现在患者随着疲乏的加重,得分呈降低趋势.结论 新辅助化疗会导致乳腺癌患者出现癌因性疲乏,同时新辅助化疗所导致的癌因性疲乏会影响乳腺癌患者的生活质量,因此,采取有效的干预措施减轻患者的疲乏以提高患者的生活质量是非常有必要的.
目的 瞭解乳腺癌患者在接受新輔助化療前後的癌因性疲乏及生活質量現狀以及癌因性疲乏與生活質量的相關性,為臨床護理榦預提供依據.方法 採用方便取樣法,對2009年11月至2010年5月北京某腫瘤醫院乳腺中心化療門診接受新輔助化療的115名乳腺癌患者,通過Piper疲乏脩訂量錶和簡明健康調查問捲進行調查.結果 新輔助化療後患者在疲乏總分[2.4(0,9.0)]、行為[1.7(0,10.0)]、情感[1.8(0,8.4)]、感知[2.2(0,10.0)]、認知情緒[1.8(0,10.0)]四箇維度得分均高于化療前[0(0,8.9),0(0,8.5),0(0,10.0),0(0,9.4),0(0,9.3)],化療前後比較,差異具有統計學意義(Z值分彆為-5.874,-5.892,-5.668,-5.712,-5.363；P＜0.01)；患者的生話質量各維度(除精神健康外)得分與新輔助化療前的得分比較差異均有統計學意義(P＜0.01)；化療後疲乏與生活質量的精力、情感職能、生理職能、社會功能、精神健康、一般健康狀況、生理機能等7箇維度得分呈負相關,錶現在患者隨著疲乏的加重,得分呈降低趨勢.結論 新輔助化療會導緻乳腺癌患者齣現癌因性疲乏,同時新輔助化療所導緻的癌因性疲乏會影響乳腺癌患者的生活質量,因此,採取有效的榦預措施減輕患者的疲乏以提高患者的生活質量是非常有必要的.
목적 료해유선암환자재접수신보조화료전후적암인성피핍급생활질량현상이급암인성피핍여생활질량적상관성,위림상호리간예제공의거.방법 채용방편취양법,대2009년11월지2010년5월북경모종류의원유선중심화료문진접수신보조화료적115명유선암환자,통과Piper피핍수정량표화간명건강조사문권진행조사.결과 신보조화료후환자재피핍총분[2.4(0,9.0)]、행위[1.7(0,10.0)]、정감[1.8(0,8.4)]、감지[2.2(0,10.0)]、인지정서[1.8(0,10.0)]사개유도득분균고우화료전[0(0,8.9),0(0,8.5),0(0,10.0),0(0,9.4),0(0,9.3)],화료전후비교,차이구유통계학의의(Z치분별위-5.874,-5.892,-5.668,-5.712,-5.363；P＜0.01)；환자적생화질량각유도(제정신건강외)득분여신보조화료전적득분비교차이균유통계학의의(P＜0.01)；화료후피핍여생활질량적정력、정감직능、생리직능、사회공능、정신건강、일반건강상황、생리궤능등7개유도득분정부상관,표현재환자수착피핍적가중,득분정강저추세.결론 신보조화료회도치유선암환자출현암인성피핍,동시신보조화료소도치적암인성피핍회영향유선암환자적생활질량,인차,채취유효적간예조시감경환자적피핍이제고환자적생활질량시비상유필요적.
Objective To describe the status of cancer-related fatigue and quality of life of breast cancer patients before and after neoadjuvant chemotherapy and provide the evidence for the clinical intervention.Methods The convenient sample was utilized.Totals of 115 breast cancer patients who received the neoadjuvant chemotherapy between November 2009 and May 2011 were investigated with the revised Piper fatigue scale Chinese version and Short Form 36 Health Survey Questionnaire.Results The total score of cancer-related fatigue,dimensions scores of total score of fatigue [2.4 (0,9.0)],behavior [1.7 (0,10.0)],emotion [1.8 (0,8.4)],perception [2.2 (0,10.0)],and cognitive emotion [1.8 (0,10.0)] of patients after neoadjuvant chemotherapy were significantly higher than that of before neoadjuvant chemotherapy [0 (0,8.9),0 (0,8.5),0 (0,10.0),0 (0,9.4),0 (0,9.3)] (Z=-5.874,-5.892,-5.668,-5.712,-5.363,respectively ;P＜0.01 ).Before and after neoadjuvant chemotherapy,significant difference was detected in the quality of life (P＜0.01 ).Cancer-related fatigue was negatively correlated with the quality of life of patients and its aspects of mental health,physical functioning,role-function,general health,vitality,social functioning,role-emotional.Conclusions Neoadjuvant chemotherapy can result the cancer-related fatigue,and cancerrelated fatigue can influence the patients' life quality.Therefore,it is necessary to apply the effective intervention in order to alleviate cancer-related fatigue and improve their life quality.
