中华现代护理杂志
中華現代護理雜誌
중화현대호리잡지
CHINESE JOURNAL OF MODERN NURSING
2013年
12期
1395-1398
,共4页
王芳%井涛%马茹%朱锦舟
王芳%井濤%馬茹%硃錦舟
왕방%정도%마여%주금주
肝硬化%酸奶%益生菌%慢性肝病问卷
肝硬化%痠奶%益生菌%慢性肝病問捲
간경화%산내%익생균%만성간병문권
Liver cirrhosis%Yogurt%Probiotic%Chronic liver disease questionnaire(CLDQ)
目的 观察富含益生菌的酸奶在改善乙肝后肝硬化患者肠道菌群失调、降低发生肝性脑病风险以及提高患者生活质量方面的作用.方法 选择乙型肝炎肝硬化患者74例,随机分为常规组38例和酸奶组36例,常规组患者给予保肝、利尿等常规治疗；酸奶组患者在此基础之上增加富含益生菌的酸奶,饭后30 min后食用.治疗2周后比较常规组和酸奶组患者慢性肝病问卷评分(CLDQ)、血粪氨含量、粪便pH值以及肠道常见菌群含量.结果 治疗后酸奶组患者CLDQ各项目评分均有提高,尤其在腹部症状、焦虑状况以及乏力方面,治疗后CLDQ评分分别为(5.78 ±0.81),(5.91±0.81),(5.66±0.61)分,治疗前分别为(4.77±0.50),(4.93±0.97),(4.89±0.67)分,治疗前后比较差异有统计学意义(t值分别为3.35,2.46,2.67;P ＜0.05)；而常规组无明显变化.酸奶组患者的血氨、粪氨浓度以及粪便pH值均下降；有益菌得到增长,致病菌菌落数减少.结论 富含益生菌酸奶可以参与乙肝后肝硬化患者的长期辅助治疗.
目的 觀察富含益生菌的痠奶在改善乙肝後肝硬化患者腸道菌群失調、降低髮生肝性腦病風險以及提高患者生活質量方麵的作用.方法 選擇乙型肝炎肝硬化患者74例,隨機分為常規組38例和痠奶組36例,常規組患者給予保肝、利尿等常規治療；痠奶組患者在此基礎之上增加富含益生菌的痠奶,飯後30 min後食用.治療2週後比較常規組和痠奶組患者慢性肝病問捲評分(CLDQ)、血糞氨含量、糞便pH值以及腸道常見菌群含量.結果 治療後痠奶組患者CLDQ各項目評分均有提高,尤其在腹部癥狀、焦慮狀況以及乏力方麵,治療後CLDQ評分分彆為(5.78 ±0.81),(5.91±0.81),(5.66±0.61)分,治療前分彆為(4.77±0.50),(4.93±0.97),(4.89±0.67)分,治療前後比較差異有統計學意義(t值分彆為3.35,2.46,2.67;P ＜0.05)；而常規組無明顯變化.痠奶組患者的血氨、糞氨濃度以及糞便pH值均下降；有益菌得到增長,緻病菌菌落數減少.結論 富含益生菌痠奶可以參與乙肝後肝硬化患者的長期輔助治療.
목적 관찰부함익생균적산내재개선을간후간경화환자장도균군실조、강저발생간성뇌병풍험이급제고환자생활질량방면적작용.방법 선택을형간염간경화환자74례,수궤분위상규조38례화산내조36례,상규조환자급여보간、이뇨등상규치료；산내조환자재차기출지상증가부함익생균적산내,반후30 min후식용.치료2주후비교상규조화산내조환자만성간병문권평분(CLDQ)、혈분안함량、분편pH치이급장도상견균군함량.결과 치료후산내조환자CLDQ각항목평분균유제고,우기재복부증상、초필상황이급핍력방면,치료후CLDQ평분분별위(5.78 ±0.81),(5.91±0.81),(5.66±0.61)분,치료전분별위(4.77±0.50),(4.93±0.97),(4.89±0.67)분,치료전후비교차이유통계학의의(t치분별위3.35,2.46,2.67;P ＜0.05)；이상규조무명현변화.산내조환자적혈안、분안농도이급분편pH치균하강；유익균득도증장,치병균균락수감소.결론 부함익생균산내가이삼여을간후간경화환자적장기보조치료.
Objective To observe the effect of probiotic yogurt in resolving enteric flora imbalance,reducing risks of hepatic encephalopathy and improving life quality of patients with liver cirrhosis after hepatitis B.Methods Totals of 74 patients with liver cirrhosis after hepatitis B were selected and randomly divided into the control group (n =38) and the yogurt group (n =36).The control group received conventional treatment to protect the liver and promote urination,while the yogurt group had probiotic yogurt 30 minutes after meals in addition.Chronic liver disease questionnaire (CLDQ) score,ammonia content in bloody stool,pH value of dejection and content of common flora were compared between two groups after two weeks of treatment.Results CLDQ score in the yogurt group improved after treatment,especially in abdominal symptoms,anxiety and acratia,which was respectively (5.78 ± 0.81),(5.91 ± 0.81) and (5.66 ± 0.61) after treatment and (4.77 ±0.50),(4.93 ± 0.97) and (4.89 ± 0.67) before.There were statistically significant differences before and after in the yogurt group (t =3.35,2.46,2.67,respectively;P ＜0.05),compared to no statistically significant difference in the control group.Content of blood ammonia and stool ammonia as well as pH value of dejection decreased in the yogurt group.Beneficial bacterium had grown and harmful bacteria had dropped.Conclusions Probiotic yogurt can take part in the long-term adjuvant treatment of patients with liver cirrhosis after hepatitis B.
