中华生物医学工程杂志
中華生物醫學工程雜誌
중화생물의학공정잡지
CHINESE JOURNAL OF BIOMEDICAL ENGINEERING
2013年
3期
246-248
,共3页
布托啡诺%芬太尼%异丙酚%流产,人工%呼吸功能不全
佈託啡諾%芬太尼%異丙酚%流產,人工%呼吸功能不全
포탁배낙%분태니%이병분%유산,인공%호흡공능불전
Butorphanol%Fentanyl%Propofol%Abortion,induced%Respiratory,insufficiency
目的 探讨布托啡诺配伍异丙酚用于无痛可视人工流产术的效果及安全可行性.方法 2011年5月本院妇科门诊自愿实施无痛人工流产术患者120例完全随机分2组,布托啡诺组和芬太尼组各60例.于麻醉诱导前5 min,布托啡诺组静脉注射布托啡诺0.02 mg/kg;芬太尼组注射芬太尼0.001 mg/kg,然后异丙酚麻醉诱导,术中以微量泵持续追加或维持,比较两组疗效及不良反应发生情况.结果 布托啡诺组止痛效果与芬太尼组比较差异无统计学意义(P＞0.05).布托啡诺组异丙酚使用总量低于芬太尼组[(139.0±12.0)比(170.0±18.5) mg,P＜0.05]；对呼吸的抑制作用较轻(P＜0.05)；呛咳反应发生率明显低于芬太尼组(P＜0.01)；术后苏醒时间明显短于芬太尼组(P＜0.05)；且无一例不良反应和并发症发生.结论 与传统方法相比,布托啡诺伍用异丙酚用于无痛可视人工流产术效果好,未见不良反应.
目的 探討佈託啡諾配伍異丙酚用于無痛可視人工流產術的效果及安全可行性.方法 2011年5月本院婦科門診自願實施無痛人工流產術患者120例完全隨機分2組,佈託啡諾組和芬太尼組各60例.于痳醉誘導前5 min,佈託啡諾組靜脈註射佈託啡諾0.02 mg/kg;芬太尼組註射芬太尼0.001 mg/kg,然後異丙酚痳醉誘導,術中以微量泵持續追加或維持,比較兩組療效及不良反應髮生情況.結果 佈託啡諾組止痛效果與芬太尼組比較差異無統計學意義(P＞0.05).佈託啡諾組異丙酚使用總量低于芬太尼組[(139.0±12.0)比(170.0±18.5) mg,P＜0.05]；對呼吸的抑製作用較輕(P＜0.05)；嗆咳反應髮生率明顯低于芬太尼組(P＜0.01)；術後囌醒時間明顯短于芬太尼組(P＜0.05)；且無一例不良反應和併髮癥髮生.結論 與傳統方法相比,佈託啡諾伍用異丙酚用于無痛可視人工流產術效果好,未見不良反應.
목적 탐토포탁배낙배오이병분용우무통가시인공유산술적효과급안전가행성.방법 2011년5월본원부과문진자원실시무통인공유산술환자120례완전수궤분2조,포탁배낙조화분태니조각60례.우마취유도전5 min,포탁배낙조정맥주사포탁배낙0.02 mg/kg;분태니조주사분태니0.001 mg/kg,연후이병분마취유도,술중이미량빙지속추가혹유지,비교량조료효급불량반응발생정황.결과 포탁배낙조지통효과여분태니조비교차이무통계학의의(P＞0.05).포탁배낙조이병분사용총량저우분태니조[(139.0±12.0)비(170.0±18.5) mg,P＜0.05]；대호흡적억제작용교경(P＜0.05)；창해반응발생솔명현저우분태니조(P＜0.01)；술후소성시간명현단우분태니조(P＜0.05)；차무일례불량반응화병발증발생.결론 여전통방법상비,포탁배낙오용이병분용우무통가시인공유산술효과호,미견불량반응.
Objective To study the efficacy and safety of butorphanol plus propofol for anesthesia in painless visible artificial abortion.Methods In May 2011,120 pregnant women who voluntarily received painless artificial abortion in our department were randomly assigned to be treated with 0.02 mg/kg butorphanol (butorphanol group,n=60) and fentanyl (fentanyl group,n=60) at 5 min prior to induced anesthesia using propofol,which were then supplemented via venous pumps during the surgery for maintenance anesthesia.The efficacy and adverse reactions were compared.Results The difference in analgesic effect was unremarkable between both groups (P＞0.05).Compared with fentanyl for anesthesia,a reduced dose was noted for butorphanol [(139.0± 12.0) vs (170.0± 18.5)mg,P＜0.05],thus resulting in minor respiratory inhibition and markedly reduced incidence of bucking (all P＜0.05).Patients treated with butorphanol yielded a shorter duration to recovery of consciousness compared with those receiving fentanyl (P＜0.05).No adverse reaction or complication was documented.Conclusion Butorphanol plus propofol has better efficacy of anesthesia in painless visible artificial abortion without adverse reactions.
