CAJ | 학술논문

心脏骤停后综合征(post-cardiac arrest syndrome,PCAS)是儿童时期常见的危重症,致死率及致残率极高,其发病机制未完全阐明,临床表现复杂多样,治疗上主要是对症支持治疗.近年来根据病理生理改变及临床预后对PCAS进行分期,并在PCAS脑损伤、心肌损伤病理生理改变及临床治疗等领域取得了一些进展.在PCAS的救治上,提倡早期亚低温治疗、控制血糖、控制惊厥和合理的心肺支持.该文就上述领域的研究作一综述,并介绍国外治疗PCAS的最新治疗策略.
심장취정후종합정(post-cardiac arrest syndrome,PCAS)시인동시기상견적위중증,치사솔급치잔솔겁고,기발병궤제미완전천명,림상표현복잡다양,치료상주요시대증지지치료.근년래근거병리생리개변급림상예후대PCAS진행분기,병재PCAS뇌손상、심기손상병리생리개변급림상치료등영역취득료일사진전.재PCAS적구치상,제창조기아저온치료、공제혈당、공제량궐화합리적심폐지지.해문취상술영역적연구작일종술,병개소국외치료PCAS적최신치료책략.
Post-cardiac arrest syndrome (PCAS) is one of the most common medical emergencies in children.The fatality rate and disability rate are extremely high.Pathogenesis of PCAS remains incompletely clear,and clinical manifestation is complicated.The treatment is mainly limited to supportive care.In recent years,the phases of PCAS are defined according to the pathophysiological changes and clinical prognosis.Investigators also made some advances in the fields of pathophysiological changes and clinical treatment of brain damage and myocardial damage.For the treatment of PCAS,early therapeutic hypothermia,glucose control and seizure control,and reasonable cardiopulmonary support are promoted.In this article,we reviewed the advances in the above fields and the latest advance on the management of PCAS in foreign countries.