CAJ | 학술논문

外科手术是治疗结直肠癌肝转移的重要手段.手术切除的适应证已扩展至满足肝内肿瘤能全部切除、切缘阴性、肝脏储备功能足够即可;而手术切除联合局部治疗进一步扩大了手术适应证.转移癌及原发癌一期或二期手术的远期生存率比较,差异无统计学意义.腹腔镜手术治疗结直肠癌肝转移安全可行,疗效确切.围手术期辅助化疗疗效并不明确,新辅助化疗可能不会使所有患者都受益.
외과수술시치료결직장암간전이적중요수단.수술절제적괄응증이확전지만족간내종류능전부절제、절연음성、간장저비공능족구즉가;이수술절제연합국부치료진일보확대료수술괄응증.전이암급원발암일기혹이기수술적원기생존솔비교,차이무통계학의의.복강경수술치료결직장암간전이안전가행,료효학절.위수술기보조화료료효병불명학,신보조화료가능불회사소유환자도수익.
Surgical resection is the treatment of choice for patients with colorectal liver metastases.The criteria for hepatic resection of colorectal liver metastases have been extended.Patients who were expected to have complete tumor resection,negative resection margin and adequate remnant liver volume could receive surgical resection.Surgical resection combined with local ablation can expand the resectability of liver metastases.There is no significant difference of long-term survival between simultaneous and staged resection for colorectal and liver tumors.Laparoscopic surgery has been proved as safe and feasible for colorectal liver metastases.The survival benefits of adjuvant chemotherapy during perioperative period is unclear,and neo-adjuvant chemotherapy might not benefit all the patients with colorectal liver metastases.