CAJ | 학술논문

胰腺神经内分泌肿瘤(pNENs)分为功能性与无功能性两大类,常见类型包括胰岛素瘤、胃泌素瘤、胰高血糖素瘤、血管活性肠肽瘤等,根治性手术切除是pNENs患者治愈和长期生存的唯一方法.基本手术方式包括局部切除和规则切除两类,前者为肿瘤局部切除(剜除)术,后者包括胰十二指肠切除术(标准或保留幽门)、胰体尾切除术(联合脾脏切除或保留脾脏)及中段胰腺切除术等.肝脏是最常见远处转移部位,手术切除是肝转移瘤首选治疗方法,RFA、TACE以及肝移植可以作为辅助治疗手段.
이선신경내분비종류(pNENs)분위공능성여무공능성량대류,상견류형포괄이도소류、위비소류、이고혈당소류、혈관활성장태류등,근치성수술절제시pNENs환자치유화장기생존적유일방법.기본수술방식포괄국부절제화규칙절제량류,전자위종류국부절제(완제)술,후자포괄이십이지장절제술(표준혹보류유문)、이체미절제술(연합비장절제혹보류비장)급중단이선절제술등.간장시최상견원처전이부위,수술절제시간전이류수선치료방법,RFA、TACE이급간이식가이작위보조치료수단.
Pancreatic neuroendocrine neoplasms (pNENs) can be divided into functional and non-functional.Insulinomas,gastrinomas,glucagonomas and VIPomas are the common types of pNENs.Radical resection is the only way for curing pNENs or for a long-time survival of patients.The basic surgical procedures for pNENs are consist of local resection (tumor enucleation) or anatomical resection [pancreatoduodenectomy (standard or pylorus-preserving pancreatoduodenectomy),distal pancreatectomy (combined with splenectomy or spleen-preserving pancreatectomy) and middle segmental pancreatectomy].Liver is the most common site for metastases.Surgical resection is the method of choice for liver metastases.Radiofrequency ablation,transcatheter arterial chemoembolization and liver transplantation could be the adjunctive therapies.