中华实验眼科杂志
中華實驗眼科雜誌
중화실험안과잡지
CHINESE JOURNAL OF EXPERIMENTAL OPHTHALMOLOGY
2012年
12期
1096-1099
,共4页
刘洋辰%王雁%李晶%左彤%王璐%鲍锡柳%魏升升
劉洋辰%王雁%李晶%左彤%王璐%鮑錫柳%魏升升
류양신%왕안%리정%좌동%왕로%포석류%위승승
飞秒激光%准分子激光角膜原位磨镶术%散射光
飛秒激光%準分子激光角膜原位磨鑲術%散射光
비초격광%준분자격광각막원위마양술%산사광
Femtosecond%Laser in situ keratomileusis%Stray light
背景 准分子激光角膜原位磨镶术(LASIK)是近年来新兴的屈光手术方式,其术后的视觉质量越来越受到关注.散射光是一项评价视觉质量的重要指标,近年来不同屈光手术前后散射光变化及其影响因素的研究是一个热点问题,研究飞秒LASIK手术后散射光的变化对术后视觉质量的评价具有重要意义.目的 观察飞秒LASIK手术前后散射光的变化,并对其影响因素进行分析. 方法 回顾性分析2010年12月至2011年2月在天津市眼科医院行飞秒LASIK的近视及近视散光患者55例109眼的临床资料,对患者术前,术后1d、1周、1个月和6个月应用C-Quant散射光计量仪测量的散射光计量值变化进行分析,并分析各时间点散射光计量值变化与术前年龄、等效球镜度、瞳孔大小和中央角膜厚度(CCT)的关系,分析术后各时间点散射光计量值变化与残余角膜植床厚度(RBT)、RBT/CCT、切削深度、切削比、设定瓣厚度、角膜瓣直径、蒂宽、能量之间的关系. 结果 飞秒LASIK术前,术后1d、1周、1个月和6个月测得的散射光计量值分别为0.90±0.19、1.10±0.19、1.02±0.18、0.96±0.16和0.94±0.15,各时间点间所测散射光计量值的总体比较差异有统计学意义(F=17.699,P=0.000),术后1周的散射光计量值明显高于术后6个月,差异有统计学意义(t=2.412,P=0.017),术后1个月与术后6个月术眼的散射光计量值差异无统计学意义(t=0.779,P=0.437),术前和术后6个月散射光计量值差异无统计学意义(t=-1.877,P=0.062).术前散射光计量值与年龄、等效球镜度、瞳孔大小和CCT均无明显相关性(P＞0.05)；术后1周、1个月及6个月散射光计量值变化与切削深度均呈负相关(r=-0.226、-0.228、-0.241,P＜0.05),与切削比均呈负相关(r=-0.149、-0.219、-0.255,P＜0.05).结论 飞秒LASIK术后1个月内散射光计量值增加,术后6个月恢复正常.术后散射光计量值的变化可能与手术中选择的多种参数和因素有关.
揹景 準分子激光角膜原位磨鑲術(LASIK)是近年來新興的屈光手術方式,其術後的視覺質量越來越受到關註.散射光是一項評價視覺質量的重要指標,近年來不同屈光手術前後散射光變化及其影響因素的研究是一箇熱點問題,研究飛秒LASIK手術後散射光的變化對術後視覺質量的評價具有重要意義.目的 觀察飛秒LASIK手術前後散射光的變化,併對其影響因素進行分析. 方法 迴顧性分析2010年12月至2011年2月在天津市眼科醫院行飛秒LASIK的近視及近視散光患者55例109眼的臨床資料,對患者術前,術後1d、1週、1箇月和6箇月應用C-Quant散射光計量儀測量的散射光計量值變化進行分析,併分析各時間點散射光計量值變化與術前年齡、等效毬鏡度、瞳孔大小和中央角膜厚度(CCT)的關繫,分析術後各時間點散射光計量值變化與殘餘角膜植床厚度(RBT)、RBT/CCT、切削深度、切削比、設定瓣厚度、角膜瓣直徑、蒂寬、能量之間的關繫. 結果 飛秒LASIK術前,術後1d、1週、1箇月和6箇月測得的散射光計量值分彆為0.90±0.19、1.10±0.19、1.02±0.18、0.96±0.16和0.94±0.15,各時間點間所測散射光計量值的總體比較差異有統計學意義(F=17.699,P=0.000),術後1週的散射光計量值明顯高于術後6箇月,差異有統計學意義(t=2.412,P=0.017),術後1箇月與術後6箇月術眼的散射光計量值差異無統計學意義(t=0.779,P=0.437),術前和術後6箇月散射光計量值差異無統計學意義(t=-1.877,P=0.062).術前散射光計量值與年齡、等效毬鏡度、瞳孔大小和CCT均無明顯相關性(P＞0.05)；術後1週、1箇月及6箇月散射光計量值變化與切削深度均呈負相關(r=-0.226、-0.228、-0.241,P＜0.05),與切削比均呈負相關(r=-0.149、-0.219、-0.255,P＜0.05).結論 飛秒LASIK術後1箇月內散射光計量值增加,術後6箇月恢複正常.術後散射光計量值的變化可能與手術中選擇的多種參數和因素有關.
배경 준분자격광각막원위마양술(LASIK)시근년래신흥적굴광수술방식,기술후적시각질량월래월수도관주.산사광시일항평개시각질량적중요지표,근년래불동굴광수술전후산사광변화급기영향인소적연구시일개열점문제,연구비초LASIK수술후산사광적변화대술후시각질량적평개구유중요의의.목적 관찰비초LASIK수술전후산사광적변화,병대기영향인소진행분석. 방법 회고성분석2010년12월지2011년2월재천진시안과의원행비초LASIK적근시급근시산광환자55례109안적림상자료,대환자술전,술후1d、1주、1개월화6개월응용C-Quant산사광계량의측량적산사광계량치변화진행분석,병분석각시간점산사광계량치변화여술전년령、등효구경도、동공대소화중앙각막후도(CCT)적관계,분석술후각시간점산사광계량치변화여잔여각막식상후도(RBT)、RBT/CCT、절삭심도、절삭비、설정판후도、각막판직경、체관、능량지간적관계. 결과 비초LASIK술전,술후1d、1주、1개월화6개월측득적산사광계량치분별위0.90±0.19、1.10±0.19、1.02±0.18、0.96±0.16화0.94±0.15,각시간점간소측산사광계량치적총체비교차이유통계학의의(F=17.699,P=0.000),술후1주적산사광계량치명현고우술후6개월,차이유통계학의의(t=2.412,P=0.017),술후1개월여술후6개월술안적산사광계량치차이무통계학의의(t=0.779,P=0.437),술전화술후6개월산사광계량치차이무통계학의의(t=-1.877,P=0.062).술전산사광계량치여년령、등효구경도、동공대소화CCT균무명현상관성(P＞0.05)；술후1주、1개월급6개월산사광계량치변화여절삭심도균정부상관(r=-0.226、-0.228、-0.241,P＜0.05),여절삭비균정부상관(r=-0.149、-0.219、-0.255,P＜0.05).결론 비초LASIK술후1개월내산사광계량치증가,술후6개월회복정상.술후산사광계량치적변화가능여수술중선택적다충삼수화인소유관.
Background As a newly developed refractive surgery,femtosecond laser in situ keratomileusis (LASIK) receives more and more attention.Changes in ocular stray light after femtosecond LASIK is an important problem that impacts visual quality.Some relevant research has been performed before,but the outcomes are conflicting.Objective This primary study was to investigate the change of stray light values before and after femtosecond LASIK and analyze the relevant factors underlying the change.Methods Clinical data from 109 eyes of 55 myopic patients who underwent femtosecond LASIK in Tianjin Eye Hospital from December,2010 through February,2011 were included in this study.Stray light values were measured and recorded by C-Quant stray light meter preoperatively,and 1 day,1 week,1 month and 6 months postoperatively.The stray light data were compared by repeated measures ANOVA,and the correlations among the stray light values with preoperative factors,such as age,equivalent sphere,pupil diameter and central corneal thickness(CCT),as well as with postoperative factors,such as residual bed thickness(RBT),RBT/CCT,ablation depth,ablation ratio,flap thickness,flap diameter flap base width and exiting energy,were analyzed statistically.Written informed consent was obtained from each individual at initial of this study.Results The stray light values were 0.90±0.19,1.10±0.19,1.02±0.18,0.96±0.16 and 0.94±0.15 pre-operation,and 1 day,1 week,1 month and 6 months after femtosecond LASIK.The stray light values increased significantly 1 day,1 week,and 1 month after surgery,showing significant differences among the various time points (F=17.699,P=0.000).The mean stray light value was higher in 1 week than that in 6 months after operation (t=2.412,P=0.017).No significant differences were found in the stray light values between 6 months and 1 month or pre-operation (t =0.779,P =0.437 ; t =-1.877,P =0.062).No significant correlations were seen between preoperative and postoperative stray light values with age,preoperative refractive diopter,pupil diameter or CCT (P＞0.05).The changes in stray light values 1 week,1 month and 6 months after surgery were negatively correlated with ablation depth(r=-0.226,-0.228,-0.241 ;P＜0.05) and ablation ratio(r =-0.149,-0.219,-0.255 ;P＜0.05).Conclusions Stray light values increase within 1 month and return to normal 6 months after femtosecond LASIK.Stray light values may be related to multiple setting laser parameters and factors during femtosecond LASIK.
