CAJ | 학술논문

炎症是一种防御反应,是干眼最常见的病理表现,而过度的炎症反应也是引起干眼常见的发病因素以及干眼进展的重要原因.抗炎药物是治疗干眼的常用药物,目前其作用机制已逐渐明确.抗炎药物的应用对缓解干眼的炎症反应具有一定的疗效,但也具有一定的不良反应,因此干眼患者局部抗炎药物的应用及其疗效的评价需要实施大样本、随机对照的多中心临床试验,以明确不同抗炎药物对不同类型干眼的治疗效果,为规范干眼的抗炎治疗提供依据.
염증시일충방어반응,시간안최상견적병리표현,이과도적염증반응야시인기간안상견적발병인소이급간안진전적중요원인.항염약물시치료간안적상용약물,목전기작용궤제이축점명학.항염약물적응용대완해간안적염증반응구유일정적료효,단야구유일정적불량반응,인차간안환자국부항염약물적응용급기료효적평개수요실시대양본、수궤대조적다중심림상시험,이명학불동항염약물대불동류형간안적치료효과,위규범간안적항염치료제공의거.
Inflammation is a defensive reaction and the most common pathological manifestation of dry eye.In addition,excessive inflammatory response is considered to be the most common pathogenic factor and main cause of dry eye.Currently,the active mechanism of anti-inflammatory drugs has been well-known,and topical antiinflammatory therapy for dry eye is exerting a role at certain extend.However,some adverse responses of these drugs are emerging during the treating procedure.Therefore,it is emphasized that a large sample size of and multicenter randomized-controlled clinical trial is needed to identify the different effects of various anti-inflammatory drugs for different types of dry eye diseases,which will offer a basis for standardized anti-inflammatory treatment for dry eye.