CAJ | 학술논문

视网膜色素上皮(RPE)细胞在维持视网膜和脉络膜的正常功能和组织结构方面发挥重要作用,许多因素可导致RPE细胞的损伤,如缺氧、物理因素、化学物质和药物、免疫因素、氧化应激等.RPE细胞的损伤可导致多种眼底疾病,引起视功能的损害或丧失.深入研究引起RPE细胞损伤的因素对各种RPE细胞相关性眼病的预防和治疗具有十分重要的意义.近年来相关的研究日益受到关注,对RPE细胞损伤的影响因素及治疗方法进行综述.
시망막색소상피(RPE)세포재유지시망막화맥락막적정상공능화조직결구방면발휘중요작용,허다인소가도치RPE세포적손상,여결양、물리인소、화학물질화약물、면역인소、양화응격등.RPE세포적손상가도치다충안저질병,인기시공능적손해혹상실.심입연구인기RPE세포손상적인소대각충RPE세포상관성안병적예방화치료구유십분중요적의의.근년래상관적연구일익수도관주,대RPE세포손상적영향인소급치료방법진행종술.
Retinal pgment epithelial (RPE) cells plays a key role in maintaining the normal physiological function and structure of retina and choroids.However,RPE cells are vulnerably damaged by many detrimental factors,such as anoxia,physical and chemical elements,pharmic,immunizing factors and oxidant stress,etc.The damage of RPE cells lead to multiple eye diseases,and therefore cause severe abnormality of visual function.To understand the causative factors of RPE cell-related eye diseases is very important for the prevention and treatment of these diseases.Recently,many studies about damage factors and treatments for RPE cells have received more attention.This article reviews the advances in RPE cell-related eye diseases.