CAJ | 학술논문

目的探讨知觉学习训练在改善青少年及成人屈光参差性弱视患者视功能方面的效果.方法前瞻性自身对照研究.共纳入18例青少年和成年单眼屈光参差性弱视患者,弱视眼在截止空间频率下进行对比度检测任务的训练,对侧相对健眼作为对照.患者随访3～6个月.分别观察患者训练前后的最佳矫正视力和对比度阈值改变,立体视改变以及试验组训练前后视觉诱发电位改变.数据进行t检验、相关性分析.结果弱视眼与相对健眼相比,其在训练前后的视力改变,截止空间频率下的对比度阈值改变,以及所有空间频率下的对比度阈值改变差异均有统计学意义(t=2.731,P＜0.05；t=5.108,P＜0.01；t=3.700,P＜0.01),弱视眼及对侧眼在训练前后潜伏期变化,振幅变化差异均无统计学意义,并且18例中有8例立体视得到改善.12例患者随访3个月,弱视眼视力平均保持了99.3％,对侧眼视力改善平均保持了50％.结论知觉学习能改善青少年及成年屈光参差性弱视患者的视功能,可用于治疗大龄弱视.
목적 탐토지각학습훈련재개선청소년급성인굴광삼차성약시환자시공능방면적효과.방법 전첨성자신대조연구.공납입18례청소년화성년단안굴광삼차성약시환자,약시안재절지공간빈솔하진행대비도검측임무적훈련,대측상대건안작위대조.환자수방3～6개월.분별관찰환자훈련전후적최가교정시력화대비도역치개변,입체시개변이급시험조훈련전후시각유발전위개변.수거진행t검험、상관성분석.결과 약시안여상대건안상비,기재훈련전후적시력개변,절지공간빈솔하적대비도역치개변,이급소유공간빈솔하적대비도역치개변차이균유통계학의의(t=2.731,P＜0.05；t=5.108,P＜0.01；t=3.700,P＜0.01),약시안급대측안재훈련전후잠복기변화,진폭변화차이균무통계학의의,병차18례중유8례입체시득도개선.12례환자수방3개월,약시안시력평균보지료99.3％,대측안시력개선평균보지료50％.결론 지각학습능개선청소년급성년굴광삼차성약시환자적시공능,가용우치료대령약시.
Objective To evaluate the effects of perceptual learning on visual acuity and contrast sensitivity function in juveniles and adults with amblyopia.Methods In this prospective self-control study,18 anisometropic amblyopes were recruited,the amblyopic eyes were trained in contrast detection near the pre-training cut-off spatial frequency.Patients were followed up for 3-6 months.Changes in the best corrected visual acuity and contrast sensitivity function and pattern visual evoked potentials and stereoacuity were measured.Data were analyzed using t test and correlation analysis.Results The amblyopic eyes had more profound changes in the visual acuity and contrast threshold (at all spatial frequencies) than the non-amblyopic fellow eyes (t=2.731,P＜0.05; t=5.108,P＜O.01;t=3.700,P＜0.01).No difference was found in the mean 60″,30″,15″ P100 latency and amplitude in both eyes after the treatment.Eight patients showed improvement in steroacuity (average 420″).The improved visual acuity was retained at 6 months in some patients.Conclusion Perceptual learning can improve the visual function of juvenile and adult amblyopia.