中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2013年
10期
624-627
,共4页
郝军生%王心凤%李兴珍%丁明红%马先生
郝軍生%王心鳳%李興珍%丁明紅%馬先生
학군생%왕심봉%리흥진%정명홍%마선생
脉络膜厚度%体层摄影术,光学相干%图像增强技术%复方托吡卡胺%散瞳
脈絡膜厚度%體層攝影術,光學相榦%圖像增彊技術%複方託吡卡胺%散瞳
맥락막후도%체층섭영술,광학상간%도상증강기술%복방탁필잡알%산동
Choroidal thickness%Tomography,optical coherence%Enhanced depth imaging%Compound tropicamide%Dilation
目的 应用频域光学相干断层扫描图像增强技术(EDI-OCT)检测轻中度近视青少年散瞳前与散瞳后,散瞳当日与次日的黄斑中心凹下脉络膜厚度的变化.方法 前瞻性临床研究.对58例(116眼)患者给予复方托吡卡胺滴眼液散瞳.散瞳前、散瞳后及散瞳次日行双眼EDI-OCT检查,以长度为8.8 mm的扫描线段对被检眼黄斑中心凹水平和垂直方位进行扫描,测量黄斑中心凹下脉络膜厚度值及黄斑中心凹处视网膜厚度值.数据采用独立样本t检验和配刘样本t检验进行分析.结果 本组患者散瞳后脉络膜厚度比散瞳前变小,差异有统计学意义(右眼:t=4.305,P＜0.01；左眼:t=5.007,P＜0.01).散瞳后络膜厚度比次日脉络膜厚度小,差异有统计学意义(右眼:t=-3.237,P＜0.01；左眼:t=-3.011,P＜0.01).散瞳前络膜厚度与次日脉络膜厚度比较,差异无统计学意义(右眼:t=-0.300,P＞0.05；左眼:t=-0.333;P＞0.05).散瞳前、散瞳后及散瞳次日双眼间视网膜各项数值比较,差异无统计学意义.结论 EDI-OCT检测到轻中度近视青少年患者在使用复方托吡卡胺滴眼液散瞳后的脉络膜变薄.该技术可以无创地、直观地观察到药物对活体组织作用引导的细微变化.
目的 應用頻域光學相榦斷層掃描圖像增彊技術(EDI-OCT)檢測輕中度近視青少年散瞳前與散瞳後,散瞳噹日與次日的黃斑中心凹下脈絡膜厚度的變化.方法 前瞻性臨床研究.對58例(116眼)患者給予複方託吡卡胺滴眼液散瞳.散瞳前、散瞳後及散瞳次日行雙眼EDI-OCT檢查,以長度為8.8 mm的掃描線段對被檢眼黃斑中心凹水平和垂直方位進行掃描,測量黃斑中心凹下脈絡膜厚度值及黃斑中心凹處視網膜厚度值.數據採用獨立樣本t檢驗和配劉樣本t檢驗進行分析.結果 本組患者散瞳後脈絡膜厚度比散瞳前變小,差異有統計學意義(右眼:t=4.305,P＜0.01；左眼:t=5.007,P＜0.01).散瞳後絡膜厚度比次日脈絡膜厚度小,差異有統計學意義(右眼:t=-3.237,P＜0.01；左眼:t=-3.011,P＜0.01).散瞳前絡膜厚度與次日脈絡膜厚度比較,差異無統計學意義(右眼:t=-0.300,P＞0.05；左眼:t=-0.333;P＞0.05).散瞳前、散瞳後及散瞳次日雙眼間視網膜各項數值比較,差異無統計學意義.結論 EDI-OCT檢測到輕中度近視青少年患者在使用複方託吡卡胺滴眼液散瞳後的脈絡膜變薄.該技術可以無創地、直觀地觀察到藥物對活體組織作用引導的細微變化.
목적 응용빈역광학상간단층소묘도상증강기술(EDI-OCT)검측경중도근시청소년산동전여산동후,산동당일여차일적황반중심요하맥락막후도적변화.방법 전첨성림상연구.대58례(116안)환자급여복방탁필잡알적안액산동.산동전、산동후급산동차일행쌍안EDI-OCT검사,이장도위8.8 mm적소묘선단대피검안황반중심요수평화수직방위진행소묘,측량황반중심요하맥락막후도치급황반중심요처시망막후도치.수거채용독립양본t검험화배류양본t검험진행분석.결과 본조환자산동후맥락막후도비산동전변소,차이유통계학의의(우안:t=4.305,P＜0.01；좌안:t=5.007,P＜0.01).산동후락막후도비차일맥락막후도소,차이유통계학의의(우안:t=-3.237,P＜0.01；좌안:t=-3.011,P＜0.01).산동전락막후도여차일맥락막후도비교,차이무통계학의의(우안:t=-0.300,P＞0.05；좌안:t=-0.333;P＞0.05).산동전、산동후급산동차일쌍안간시망막각항수치비교,차이무통계학의의.결론 EDI-OCT검측도경중도근시청소년환자재사용복방탁필잡알적안액산동후적맥락막변박.해기술가이무창지、직관지관찰도약물대활체조직작용인도적세미변화.
Objective To study the choroidal thickness of the macula subfovea using enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT) before dilation,after dilation,the following day after dilation.Methods Prospective clinical study.Fifty-eight patients (116 eyes) were dilated with tropicamide eye drops.All patients were examined with EDI-OCT before dilation,after dilation and the following day after dilation.Then,the eyes were scanned with a 8.8 mm scan line in the horizontal and vertical directions.Finally,the subfoveal choroidal thickness and the retinal thickness of the fovea were measured.Data were analyzed using independent t test and paired t test.Results Choroidal thickness after dilation was thinner than before dilation.The difference was statistically significant (right eye:t=4.305,P＜0.01; left eye:t=5.007,P＜0.01).Choroidal thickness after dilation was thinner than that measured the next day after dilation,and the difference was statistically significant (right eye:t=-3.237,P＜0.01; left eye:t=-3.011,P＜0.01).However,the difference between choroidal thickness before dilation and the next day after dilation was not statistically significant (right eye:t=-0.300,P＞0.05; left eye:t=-0.333,P＞0.05).There was no significant difference between binocular retinal values measured before dilation,after dilation,or the following day after dilation.Conclusion The choroid becomes thinner after using tropicamide eye drops when measured by EDI-OCT,which is noninvasive and intuitive to observe the subtle changes in living tissue after drug use.
