中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2014年
2期
84-87
,共4页
角膜塑形术%眼轴%屈光,眼,周边%瞳孔直径
角膜塑形術%眼軸%屈光,眼,週邊%瞳孔直徑
각막소형술%안축%굴광,안,주변%동공직경
Orthokeratology%Axial length%Refractive,ocular peripheral%Pupil diameter
目的 观察瞳孔直径对角膜塑形镜近视控制作用的影响.方法 前瞻性研究.7~14岁低中度青少年近视患者49例(49眼),分别进行综合验光、瞳孔直径以及眼轴等检查,并按照角膜塑形镜的验配程序予以配戴,并测量戴镜前和2年后患者的眼轴长度及瞳孔直径.将瞳孔直径的均值作为分割点将患者分为2组:瞳孔直径低于均值组(26例)和瞳孔直径高于均值组(23例).采用配对t检验、独立样本t检验、重复测量方差分析以及Pearson相关分析对数据进行分析.结果 配戴角膜塑形镜2年内,眼轴显著增长(F=67.182,P<0.01).瞳孔直径低于均值组与瞳孔直径高于均值组的眼轴增长分别为(0.43±0.28)mm、(0.24±0.27)mm,差异有统计学意义(t=2.379,P<0.05),瞳孔直径高于均值组的眼轴增长量仅为瞳孔直径低于均值组的55.81%.初始瞳孔直径与2年眼轴增长之间呈显著负相关(r=-0.361,P<0.05).且得出瞳孔直径与眼轴增长之间的回归方程为:眼轴增长=-0.161×瞳孔直径±0.987(F=7.048,P<0.05).瞳孔直径高于均值组2年后的瞳孔直径为(3.72±0.53)mm,而瞳孔直径低于均值组的为(3.51±0.37)mm,2组之间差异无统计学意义(t=2.543,P>0.05).结论 配戴角膜塑形镜后,瞳孔直径大的青少年近视患者可以获得更好的近视控制效果.这可能是由于大的瞳孔可以增强近视周边屈光对眼轴控制的积极作用.
目的 觀察瞳孔直徑對角膜塑形鏡近視控製作用的影響.方法 前瞻性研究.7~14歲低中度青少年近視患者49例(49眼),分彆進行綜閤驗光、瞳孔直徑以及眼軸等檢查,併按照角膜塑形鏡的驗配程序予以配戴,併測量戴鏡前和2年後患者的眼軸長度及瞳孔直徑.將瞳孔直徑的均值作為分割點將患者分為2組:瞳孔直徑低于均值組(26例)和瞳孔直徑高于均值組(23例).採用配對t檢驗、獨立樣本t檢驗、重複測量方差分析以及Pearson相關分析對數據進行分析.結果 配戴角膜塑形鏡2年內,眼軸顯著增長(F=67.182,P<0.01).瞳孔直徑低于均值組與瞳孔直徑高于均值組的眼軸增長分彆為(0.43±0.28)mm、(0.24±0.27)mm,差異有統計學意義(t=2.379,P<0.05),瞳孔直徑高于均值組的眼軸增長量僅為瞳孔直徑低于均值組的55.81%.初始瞳孔直徑與2年眼軸增長之間呈顯著負相關(r=-0.361,P<0.05).且得齣瞳孔直徑與眼軸增長之間的迴歸方程為:眼軸增長=-0.161×瞳孔直徑±0.987(F=7.048,P<0.05).瞳孔直徑高于均值組2年後的瞳孔直徑為(3.72±0.53)mm,而瞳孔直徑低于均值組的為(3.51±0.37)mm,2組之間差異無統計學意義(t=2.543,P>0.05).結論 配戴角膜塑形鏡後,瞳孔直徑大的青少年近視患者可以穫得更好的近視控製效果.這可能是由于大的瞳孔可以增彊近視週邊屈光對眼軸控製的積極作用.
목적 관찰동공직경대각막소형경근시공제작용적영향.방법 전첨성연구.7~14세저중도청소년근시환자49례(49안),분별진행종합험광、동공직경이급안축등검사,병안조각막소형경적험배정서여이배대,병측량대경전화2년후환자적안축장도급동공직경.장동공직경적균치작위분할점장환자분위2조:동공직경저우균치조(26례)화동공직경고우균치조(23례).채용배대t검험、독립양본t검험、중복측량방차분석이급Pearson상관분석대수거진행분석.결과 배대각막소형경2년내,안축현저증장(F=67.182,P<0.01).동공직경저우균치조여동공직경고우균치조적안축증장분별위(0.43±0.28)mm、(0.24±0.27)mm,차이유통계학의의(t=2.379,P<0.05),동공직경고우균치조적안축증장량부위동공직경저우균치조적55.81%.초시동공직경여2년안축증장지간정현저부상관(r=-0.361,P<0.05).차득출동공직경여안축증장지간적회귀방정위:안축증장=-0.161×동공직경±0.987(F=7.048,P<0.05).동공직경고우균치조2년후적동공직경위(3.72±0.53)mm,이동공직경저우균치조적위(3.51±0.37)mm,2조지간차이무통계학의의(t=2.543,P>0.05).결론 배대각막소형경후,동공직경대적청소년근시환자가이획득경호적근시공제효과.저가능시유우대적동공가이증강근시주변굴광대안축공제적적겁작용.
Objective To evaluate the impact of pupil diameter on controlling the development of myopia in orthokeratology.Methods Forty-nine children aged 7 to 14 years were enrolled in this prospective clinical study.Orthokeratology was performed to correct the refractive errors of these children after measurements of refraction,pupil diameter and axial length.Axial length (AL) and pupil diameter were measured 24 months after lens wearing.The average pupil diameter was calculated and was used as the criterion for dividing the children into "pupil size above average"vs "pupil size below average".Data were analyzed by a paired t-test,an independent t-test,repeated measured ANOVAs and Pearson correlation analysis.Results AL increased significantly throughout the 24-month observation period (F=67.182,P<0.01).The axial growth of subjects with below average pupil sizes and those with above average pupil sizes was 0.43±0.28 mm and 0.24±0.27 mm,indicating a statistically significant difference (t=2.379,P<0.05).AL change in subjects with above average pupil diameters was 55.81% of that for subjects with below average pupil diameters.Baseline pupil diameter was negatively correlated with axial growth at the 24-month visit (r=-0.361,P<0.05).Linear regression analysis was used between baseline pupil diameter and 2-year axial growth:Axial growth=-0.161× baseline pupil diameter +0.987 (F=7.048,P<0.05).The average pupil diameter for subjects with above average pupil sizes and those with below average pupil sizes after 2 years was 3.72±0.53 mm and 3.51±0.37 mm,indicating no statistically significant difference (t=2.543,P>0.05).Conclusion The effect of orthokeratology to control myopia would be more beneficial for children with larger pupil diameters than for children with smaller pupil diameters.This may be due to the enhancement of the myopic shift in the peripheral retina.