中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2014年
5期
287-290
,共4页
周佳奇%李梅%钟元园%周行涛%褚仁远
週佳奇%李梅%鐘元園%週行濤%褚仁遠
주가기%리매%종원완%주행도%저인원
生物力学%近视%角膜塑形术%角膜曲率
生物力學%近視%角膜塑形術%角膜麯率
생물역학%근시%각막소형술%각막곡솔
Biomechanics%Myopia%Orthokeratology%Corneal curvature
目的 探讨角膜生物力学性能与角膜塑形术后角膜曲率变化的相关性.方法 前瞻性研究.选取复旦大学附属眼耳鼻喉科医院接触镜室就诊的青少年近视患者29例(57眼),平均年龄(9.7±2.1)岁,等效球镜度范围-1.00～-4.75 D,验配前进行眼科常规检查、屈光检查、Oculus Pentacam 三维眼前节分析仪测量角膜地形图、Canon角膜曲率计测量角膜平坦K1及陡峭K2、眼反应分析仪测量角膜生物力学性能包括角膜滞后量(CH)及角膜阻力因子(CRF).根据角膜中央K值及e值采用经验法进行镜片验配.分别于戴镜1d及7d后进行角膜曲率测量,测得角膜平坦K1及陡峭K2.对戴镜前、戴镜后1 d、戴镜后7d的视力、角膜曲率进行方差分析,并分别对CH及CRF值与戴镜1d、7d后角膜曲率变化值相关性进行分析.结果 配戴1 d后角膜曲率平坦K1由(42.76±0.78)D下降到(41.78±0.86)D,戴镜7d后下降为(40.52±1.26)D(F=71.962,P＜0.05),戴镜1 d后陡峭K2由(43.91±0.81)D下降到(43.34±0.89)D,戴镜7d后下降到(42.14±1.44)D(F=40.602,P＜0.05),不同时间点间差异均存在统计学意义.相关性分析结果显示,角膜生物力学参数CH、CRF值与戴镜后1d、7d角膜曲率平坦K1、陡峭K2的变化均不存在相关性.结论 角膜生物力学参数CH及CRF值在角膜塑形术角膜重塑过程中所起到的作用未得到证实.
目的 探討角膜生物力學性能與角膜塑形術後角膜麯率變化的相關性.方法 前瞻性研究.選取複旦大學附屬眼耳鼻喉科醫院接觸鏡室就診的青少年近視患者29例(57眼),平均年齡(9.7±2.1)歲,等效毬鏡度範圍-1.00～-4.75 D,驗配前進行眼科常規檢查、屈光檢查、Oculus Pentacam 三維眼前節分析儀測量角膜地形圖、Canon角膜麯率計測量角膜平坦K1及陡峭K2、眼反應分析儀測量角膜生物力學性能包括角膜滯後量(CH)及角膜阻力因子(CRF).根據角膜中央K值及e值採用經驗法進行鏡片驗配.分彆于戴鏡1d及7d後進行角膜麯率測量,測得角膜平坦K1及陡峭K2.對戴鏡前、戴鏡後1 d、戴鏡後7d的視力、角膜麯率進行方差分析,併分彆對CH及CRF值與戴鏡1d、7d後角膜麯率變化值相關性進行分析.結果 配戴1 d後角膜麯率平坦K1由(42.76±0.78)D下降到(41.78±0.86)D,戴鏡7d後下降為(40.52±1.26)D(F=71.962,P＜0.05),戴鏡1 d後陡峭K2由(43.91±0.81)D下降到(43.34±0.89)D,戴鏡7d後下降到(42.14±1.44)D(F=40.602,P＜0.05),不同時間點間差異均存在統計學意義.相關性分析結果顯示,角膜生物力學參數CH、CRF值與戴鏡後1d、7d角膜麯率平坦K1、陡峭K2的變化均不存在相關性.結論 角膜生物力學參數CH及CRF值在角膜塑形術角膜重塑過程中所起到的作用未得到證實.
목적 탐토각막생물역학성능여각막소형술후각막곡솔변화적상관성.방법 전첨성연구.선취복단대학부속안이비후과의원접촉경실취진적청소년근시환자29례(57안),평균년령(9.7±2.1)세,등효구경도범위-1.00～-4.75 D,험배전진행안과상규검사、굴광검사、Oculus Pentacam 삼유안전절분석의측량각막지형도、Canon각막곡솔계측량각막평탄K1급두초K2、안반응분석의측량각막생물역학성능포괄각막체후량(CH)급각막조력인자(CRF).근거각막중앙K치급e치채용경험법진행경편험배.분별우대경1d급7d후진행각막곡솔측량,측득각막평탄K1급두초K2.대대경전、대경후1 d、대경후7d적시력、각막곡솔진행방차분석,병분별대CH급CRF치여대경1d、7d후각막곡솔변화치상관성진행분석.결과 배대1 d후각막곡솔평탄K1유(42.76±0.78)D하강도(41.78±0.86)D,대경7d후하강위(40.52±1.26)D(F=71.962,P＜0.05),대경1 d후두초K2유(43.91±0.81)D하강도(43.34±0.89)D,대경7d후하강도(42.14±1.44)D(F=40.602,P＜0.05),불동시간점간차이균존재통계학의의.상관성분석결과현시,각막생물역학삼수CH、CRF치여대경후1d、7d각막곡솔평탄K1、두초K2적변화균불존재상관성.결론 각막생물역학삼수CH급CRF치재각막소형술각막중소과정중소기도적작용미득도증실.
Objective To investigate the correlation between corneal biomechanical properties and the changes in corneal curvature when undergoing orthokeratology.Methods Fifty-seven eyes of 29 subjects with-1.00--4.75 D of myopia wore overnight reverse-geometry rigid gas-permeable lenses were included in this prospective study.The clinical examination included refractive error,uncorrected and best corrected visual acuity,and slit-lamp examination and were recorded in detail.Corneal resistance factor (CRF) and corneal hysteresis (CH) were measured with an ocular response analyzer.Corneal topography was measured with an Oculus Pentacam analysis system at pre-wear.Keratometric curvature (steep and fiat K values) was measured pre-wear,and 1 day and 7 days post-wear.A one-way ANOVA and correlation analysis were used for statistical analysis.Results The fiat keratornetric curvatures (K1) were significantly reduced from 42.76±0.78 D (baseline) to 41.78±0.86 D after one night of wear,and 40.52±1.26 D after 7 nights of wear (F=71.962,P＜0.01).The steep keratometric curvatures (K2) were significantly reduced from 43.91±0.81 D (baseline) to 43.34±0.89 D after one night of wear,and 42.14±1.44 D after 7 nights of wear (F=40.602,P＜0.01).CRF and CH did not correlate significantly with the reduction of K1 and K2,respectively,after 1 and 7 nights of wear.Conclusion This study indicates that the biomechanical properties CRF and CH did not correlate with the changes in corneal curvature while undergoing orthokeratology.
