中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2008年
22期
9-11
,共3页
张弘%王明涛%王晓英%李雪松%张博%姜世满
張弘%王明濤%王曉英%李雪鬆%張博%薑世滿
장홍%왕명도%왕효영%리설송%장박%강세만
增生%胃肿瘤%胃镜%随访研究
增生%胃腫瘤%胃鏡%隨訪研究
증생%위종류%위경%수방연구
Hyperplasia%Stomach neoplasms%Gastroscopes%Follow-up studies
目的 探讨胃黏膜上皮细胞异型增生与胃癌发生的关系、演变规律. 方法 对189例伴有异型增生胃部病变患者用胃镜随访复查,对不同程度异型增生的变化和转归资料进行回顾性分析. 结果 胃镜观察189例伴异型增生的病灶主要分布在胃体和胃窦.随访时间6个月至8.3年,平均(3.41±2.53)年,随访结果异型增生消退134例占70.9%,其中,轻、中、重度异型增生消退率分别为85.7%、49.0%、36.8%,轻、中、重度异型增生消退时间分别为(1.36±0.62)、(2.54±1.85)、(2.37±1.76)年.189例胃黏膜上皮细胞异型增生患者癌变15例,癌变率为7.9%,轻、中、重度异型增生癌变率分别为1.7%、9.8%、42.1%,15例胃癌中早期胃癌6例占40.0%. 结论 胃黏膜上皮细胞异型增生具有不容忽视的癌变倾向,重度异型增生癌变率高,用胃镜定期随访复查可提高早期胃癌检出率,在临床工作中应普遍开展.
目的 探討胃黏膜上皮細胞異型增生與胃癌髮生的關繫、縯變規律. 方法 對189例伴有異型增生胃部病變患者用胃鏡隨訪複查,對不同程度異型增生的變化和轉歸資料進行迴顧性分析. 結果 胃鏡觀察189例伴異型增生的病竈主要分佈在胃體和胃竇.隨訪時間6箇月至8.3年,平均(3.41±2.53)年,隨訪結果異型增生消退134例佔70.9%,其中,輕、中、重度異型增生消退率分彆為85.7%、49.0%、36.8%,輕、中、重度異型增生消退時間分彆為(1.36±0.62)、(2.54±1.85)、(2.37±1.76)年.189例胃黏膜上皮細胞異型增生患者癌變15例,癌變率為7.9%,輕、中、重度異型增生癌變率分彆為1.7%、9.8%、42.1%,15例胃癌中早期胃癌6例佔40.0%. 結論 胃黏膜上皮細胞異型增生具有不容忽視的癌變傾嚮,重度異型增生癌變率高,用胃鏡定期隨訪複查可提高早期胃癌檢齣率,在臨床工作中應普遍開展.
목적 탐토위점막상피세포이형증생여위암발생적관계、연변규률. 방법 대189례반유이형증생위부병변환자용위경수방복사,대불동정도이형증생적변화화전귀자료진행회고성분석. 결과 위경관찰189례반이형증생적병조주요분포재위체화위두.수방시간6개월지8.3년,평균(3.41±2.53)년,수방결과이형증생소퇴134례점70.9%,기중,경、중、중도이형증생소퇴솔분별위85.7%、49.0%、36.8%,경、중、중도이형증생소퇴시간분별위(1.36±0.62)、(2.54±1.85)、(2.37±1.76)년.189례위점막상피세포이형증생환자암변15례,암변솔위7.9%,경、중、중도이형증생암변솔분별위1.7%、9.8%、42.1%,15례위암중조기위암6례점40.0%. 결론 위점막상피세포이형증생구유불용홀시적암변경향,중도이형증생암변솔고,용위경정기수방복사가제고조기위암검출솔,재림상공작중응보편개전.
Objective To study the relation and evolvement rule between gastric epithelial cells and gastric cancer dysplasia.Method Different degrees of 189 patients with gastric epithelial cell dysplasia in dysplasia changes and outcome from the follow-up with gastroscope reexamination were retrospectively analyzed.Results Allotype hyperplastic lesions in 189 patients mainly distributed at gastric body and sinus.The shortest follow-up time was six months,the longest was 8.3 years,and the average follow-up time was (3.41±2.53)years.Allotype hyperplasia in 70.9%of 189 patients regressed in the end of follow-up.Among them,the regression rate of mild,medium and serious allotype hyperplasia Was respectively 85.7%,49.0%,36.8%,andthe regression time was(1.36±0.62),(2.54±1.85),(2.37±1.76)years respectively.Canceration rate was 7.9%(15 cases)in 189 patients with allotype hyperplasia.It Was 1.7%,9.8%and 42.1%respectively in patienm with mild,medium and serious allotype hyperplasia.There was 40.0%(6 cases)of 15 patients with gastric cancer belonged to the early stage.Conclusions There is an innegligible tendency of canceration and higher canceration rate of serious lesions in allotype hyperplasia.So it should be paid attention to and treated intensively.The discovering rate of early gastric cancer would be improved by regular follow-up with endoscopy review practicing in clinical work.
