中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2013年
6期
12-15
,共4页
婴儿,早产%感染%危险因素
嬰兒,早產%感染%危險因素
영인,조산%감염%위험인소
Infant,premature%Infection%Risk factors
目的 探讨早产儿外周中心静脉置管(PICC)相关性感染的发生率、危险因素,以利于实施预防措施,有效控制感染的发生.方法 258例出生体重小于2.5 kg行PICC的早产儿,根据有无发生导管相关性感染(CRI)分为CRI组与非CRI组,把两组胎龄、出生体重、PICC时间、胃肠外营养时间和PICC时胃肠外营养时间进行统计学分析以及比较不同置管时间CRI发生情况.结果 确诊CRI 24例,发生率9.3％(24/258).CRI组平均胎龄、出生体重、PICC时间、胃肠外营养时间、PICC时胃肠外营养时间分别为29.5周、1.4 kg、31.5 d、40.1 d、28.8 d,非CRI组分别为33.0周、1.8 kg、14.6 d、16.7 d、13.4 d,两组比较差异有统计学意义(P＜0.01或＜0.05).不同置管时间CRI发生率比较差异有统计学意义(P＜0.01).发生CRI的危险因素包括胎龄(P=0.007)、出生体重(P=0.000)、PICC时间(P=0.001)、胃肠外营养时间(P=0.035)、PICC时胃肠外营养时间(P=0.001).多因素Logistic回归分析显示影响最大的3个因素是出生体重、胃肠外营养时间、胎龄.结论 胎龄、出生体重、PICC时间、胃肠外营养时间是导致PICC患儿发生CRI的危险因素.
目的 探討早產兒外週中心靜脈置管(PICC)相關性感染的髮生率、危險因素,以利于實施預防措施,有效控製感染的髮生.方法 258例齣生體重小于2.5 kg行PICC的早產兒,根據有無髮生導管相關性感染(CRI)分為CRI組與非CRI組,把兩組胎齡、齣生體重、PICC時間、胃腸外營養時間和PICC時胃腸外營養時間進行統計學分析以及比較不同置管時間CRI髮生情況.結果 確診CRI 24例,髮生率9.3％(24/258).CRI組平均胎齡、齣生體重、PICC時間、胃腸外營養時間、PICC時胃腸外營養時間分彆為29.5週、1.4 kg、31.5 d、40.1 d、28.8 d,非CRI組分彆為33.0週、1.8 kg、14.6 d、16.7 d、13.4 d,兩組比較差異有統計學意義(P＜0.01或＜0.05).不同置管時間CRI髮生率比較差異有統計學意義(P＜0.01).髮生CRI的危險因素包括胎齡(P=0.007)、齣生體重(P=0.000)、PICC時間(P=0.001)、胃腸外營養時間(P=0.035)、PICC時胃腸外營養時間(P=0.001).多因素Logistic迴歸分析顯示影響最大的3箇因素是齣生體重、胃腸外營養時間、胎齡.結論 胎齡、齣生體重、PICC時間、胃腸外營養時間是導緻PICC患兒髮生CRI的危險因素.
목적 탐토조산인외주중심정맥치관(PICC)상관성감염적발생솔、위험인소,이리우실시예방조시,유효공제감염적발생.방법 258례출생체중소우2.5 kg행PICC적조산인,근거유무발생도관상관성감염(CRI)분위CRI조여비CRI조,파량조태령、출생체중、PICC시간、위장외영양시간화PICC시위장외영양시간진행통계학분석이급비교불동치관시간CRI발생정황.결과 학진CRI 24례,발생솔9.3％(24/258).CRI조평균태령、출생체중、PICC시간、위장외영양시간、PICC시위장외영양시간분별위29.5주、1.4 kg、31.5 d、40.1 d、28.8 d,비CRI조분별위33.0주、1.8 kg、14.6 d、16.7 d、13.4 d,량조비교차이유통계학의의(P＜0.01혹＜0.05).불동치관시간CRI발생솔비교차이유통계학의의(P＜0.01).발생CRI적위험인소포괄태령(P=0.007)、출생체중(P=0.000)、PICC시간(P=0.001)、위장외영양시간(P=0.035)、PICC시위장외영양시간(P=0.001).다인소Logistic회귀분석현시영향최대적3개인소시출생체중、위장외영양시간、태령.결론 태령、출생체중、PICC시간、위장외영양시간시도치PICC환인발생CRI적위험인소.
Objective To study the incidence rate and risk factors of catheter-related infection (CRI) in preemie with peripherally inserted central catheter (PICC),in order to facilitate the implementation of control strategies and control infection.Methods Two hundred and fifty-eight PICC preemie of birth weight less than 2.5 kg,according to whether the incidence of CRI were divided into CRI group and non CRI group,two groups of gestational age,birth weight,PICC time,parenteral nutrition time and PICC parenteral nutrition time were statistically analyzed and compared different indwelling time of CRI incidence.Results Diagnosis of CRI in 24 cases,the occurrence rate of 9.3％ (24/258).There were significant differences in gestational age,birth weight,PICC time,parenteral nutrition time,PICC parenteral nutrition time between CRI group aad non CRI group (29.5 weeks vs.33.0 weeks,1.4 kg vs.1.8 kg,31.5 days vs.14.6 days,40.1 days vs.16.7 days,28.8 days vs.13.4 days,P ＜ 0.01 or ＜ 0.05).There was significant difference in incidence rate of CRI among different indwelling time (P ＜ 0.01).The risk factors of CRI including gestational age (P =0.007),birth weight (P=0.000),PICC time (P=0.001),parenteral nutrition time (P=0.035),PICC parenteral nutrition time (P =0.001).Multivariate Logistic regression analysis showed the greatest impact on the 3 factors were birth weight,parenteral nutrition time,gestational age.Conclusion Gestational age,birth weight,PICC time,parenteral nutrition time are the risk factors of CRI in preemie with PICC.
