中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2013年
7期
21-23
,共3页
杨传高%陆卫红%鲍小京%薄小萍%羊镇宇
楊傳高%陸衛紅%鮑小京%薄小萍%羊鎮宇
양전고%륙위홍%포소경%박소평%양진우
血红蛋白类%血糖%心肌梗死
血紅蛋白類%血糖%心肌梗死
혈홍단백류%혈당%심기경사
Hemoglobins%Blood glucose%Myocardial infarction
目的 比较糖化血红蛋白(HbA1c)及入院时血糖对无糖尿病病史急性ST段抬高性心肌梗死的近期预后价值.方法 选取2010年1月至2011年6月住院的无糖尿病病史急性ST段抬高性心肌梗死患者84例,测定HbA1c及入院时血糖,随访30 d内的心血管事件.结果 以所测得的HbA1c及入院时血糖的均值为截断点,按HbA1c水平分为HbA1c<5.5%组40例及HbA1c≥5.5%组44例,按入院时血糖水平分为人院时血糖≤8.6 mmol/L组42例及入院时血糖>8.6mmo1/L组42例.入院时血糖>8.6mmol/L组随访30 d内的心血管事件发生率高于入院时血糖≤8.6mmol/L组[19.0%(8/42)比2.4%(1/42)],差异有统计学意义(P<0.05).HbA1c≥5.5%组随访30 d内的心血管事件发生率与HbA1c<5.5%组比较差异无统计学意义(P>0.05).入院时血糖与血肌酸激酶同工酶MB峰值有弱相关性(r=0.233,P<0.05).结论 入院时血糖升高预示无糖尿病病史急性ST段抬高性心肌梗死的近期心血管事件增多.
目的 比較糖化血紅蛋白(HbA1c)及入院時血糖對無糖尿病病史急性ST段抬高性心肌梗死的近期預後價值.方法 選取2010年1月至2011年6月住院的無糖尿病病史急性ST段抬高性心肌梗死患者84例,測定HbA1c及入院時血糖,隨訪30 d內的心血管事件.結果 以所測得的HbA1c及入院時血糖的均值為截斷點,按HbA1c水平分為HbA1c<5.5%組40例及HbA1c≥5.5%組44例,按入院時血糖水平分為人院時血糖≤8.6 mmol/L組42例及入院時血糖>8.6mmo1/L組42例.入院時血糖>8.6mmol/L組隨訪30 d內的心血管事件髮生率高于入院時血糖≤8.6mmol/L組[19.0%(8/42)比2.4%(1/42)],差異有統計學意義(P<0.05).HbA1c≥5.5%組隨訪30 d內的心血管事件髮生率與HbA1c<5.5%組比較差異無統計學意義(P>0.05).入院時血糖與血肌痠激酶同工酶MB峰值有弱相關性(r=0.233,P<0.05).結論 入院時血糖升高預示無糖尿病病史急性ST段抬高性心肌梗死的近期心血管事件增多.
목적 비교당화혈홍단백(HbA1c)급입원시혈당대무당뇨병병사급성ST단태고성심기경사적근기예후개치.방법 선취2010년1월지2011년6월주원적무당뇨병병사급성ST단태고성심기경사환자84례,측정HbA1c급입원시혈당,수방30 d내적심혈관사건.결과 이소측득적HbA1c급입원시혈당적균치위절단점,안HbA1c수평분위HbA1c<5.5%조40례급HbA1c≥5.5%조44례,안입원시혈당수평분위인원시혈당≤8.6 mmol/L조42례급입원시혈당>8.6mmo1/L조42례.입원시혈당>8.6mmol/L조수방30 d내적심혈관사건발생솔고우입원시혈당≤8.6mmol/L조[19.0%(8/42)비2.4%(1/42)],차이유통계학의의(P<0.05).HbA1c≥5.5%조수방30 d내적심혈관사건발생솔여HbA1c<5.5%조비교차이무통계학의의(P>0.05).입원시혈당여혈기산격매동공매MB봉치유약상관성(r=0.233,P<0.05).결론 입원시혈당승고예시무당뇨병병사급성ST단태고성심기경사적근기심혈관사건증다.
Objective To compare the short-term prognostic value of glycohemoglobin (HbA1c) and admission plasma glucose in non-diabetic patients with acute ST-elevation myocardial infarction.Methods Eighty-four non-diabetic patients with acute ST-elevation myocardial infarction from January 2010 to June 2011 were included.Both HbA1c and plasma glucose was measured on admission.Cardiovascular event was followed up in 30 days.Results The average of HbA1c and admission plasma glucose was as cut-off point.The patients were divided into HbA1c < 5.5% group (40 cases) and HbA1c ≥5.5% group (44 cases) according to HbA1c level.The patients were divided into admission plasma glucose ≤ 8.6 mmol/L group (42 cases) and admission plasma glucose > 8.6 mmol/L group (42 cases) according to admission plasma glucose.The incidence of cardiovascular event in 30 days in admission plasma glucose > 8.6 mmol/L group was higher than that in admission plasma glucose ≤ 8.6 mmol/L group [19.0% (8/42) vs.2.4% (1/42)],and there was significant difference(P< 0.05).There was no significant difference in the incidence of cardiovascular event in 30 days between HbA1c ≥5.5% group and HbA1c < 5.5% group (P > 0.05).Admission plasma glucose showed weak correlation with blood creatine kinase isoenzyme MB peak (r =0.233,P <0.05).Conclusion In non-diabetic patients with acute ST-elevation myocardial infarction,elevated admission plasma glucose levels are associated with higher cardiovascular event in 30 days.