中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2013年
10期
28-31
,共4页
张捷%陈海亮%张林艳%许多
張捷%陳海亮%張林豔%許多
장첩%진해량%장림염%허다
脑梗塞%复发%危险因素%Meta分析
腦梗塞%複髮%危險因素%Meta分析
뇌경새%복발%위험인소%Meta분석
Brain infarction%Recurrence%Risk factors%Meta analysis
目的 综合评价中国人复发性脑梗死的危险因素.方法 通过计算机文献检索(中国期刊全文数据库、维普中文科技期刊全文数据库、万方数据库),以及采用文献追溯等方法,收集国内于2011年12月前发表的关于复发性脑梗死危险因素的研究文献.采用STATA 11.0软件,应用Meta分析的方法对结果进行定量综合分析.结果 共检索到216篇文献,根据纳入与排除标准进行筛选,共有12篇文献纳入本研究,全部为病例-对照研究.累计病例1599例,对照2566例.Meta分析结果表明,性别、高血压、糖尿病、高脂血症、吸烟和年龄的合并效应量(95％可信区间)分别为1.58(1.04～ 2.39)、2.66 (2.02～3.51)、2.23 (1.70～2.93)、2.22 (1.48 ～3.32)、1.94(1.64～ 2.29)和1.58(0.55～ 2.60),经Z检验差异均有统计学意义(Z=2.16、6.95、5.82、3.87、7.68和3.02,P值均＜0.05).结论 高血压、糖尿病、高脂血症、吸烟、男性和年龄是复发性脑梗死的危险因素.
目的 綜閤評價中國人複髮性腦梗死的危險因素.方法 通過計算機文獻檢索(中國期刊全文數據庫、維普中文科技期刊全文數據庫、萬方數據庫),以及採用文獻追溯等方法,收集國內于2011年12月前髮錶的關于複髮性腦梗死危險因素的研究文獻.採用STATA 11.0軟件,應用Meta分析的方法對結果進行定量綜閤分析.結果 共檢索到216篇文獻,根據納入與排除標準進行篩選,共有12篇文獻納入本研究,全部為病例-對照研究.纍計病例1599例,對照2566例.Meta分析結果錶明,性彆、高血壓、糖尿病、高脂血癥、吸煙和年齡的閤併效應量(95％可信區間)分彆為1.58(1.04～ 2.39)、2.66 (2.02～3.51)、2.23 (1.70～2.93)、2.22 (1.48 ～3.32)、1.94(1.64～ 2.29)和1.58(0.55～ 2.60),經Z檢驗差異均有統計學意義(Z=2.16、6.95、5.82、3.87、7.68和3.02,P值均＜0.05).結論 高血壓、糖尿病、高脂血癥、吸煙、男性和年齡是複髮性腦梗死的危險因素.
목적 종합평개중국인복발성뇌경사적위험인소.방법 통과계산궤문헌검색(중국기간전문수거고、유보중문과기기간전문수거고、만방수거고),이급채용문헌추소등방법,수집국내우2011년12월전발표적관우복발성뇌경사위험인소적연구문헌.채용STATA 11.0연건,응용Meta분석적방법대결과진행정량종합분석.결과 공검색도216편문헌,근거납입여배제표준진행사선,공유12편문헌납입본연구,전부위병례-대조연구.루계병례1599례,대조2566례.Meta분석결과표명,성별、고혈압、당뇨병、고지혈증、흡연화년령적합병효응량(95％가신구간)분별위1.58(1.04～ 2.39)、2.66 (2.02～3.51)、2.23 (1.70～2.93)、2.22 (1.48 ～3.32)、1.94(1.64～ 2.29)화1.58(0.55～ 2.60),경Z검험차이균유통계학의의(Z=2.16、6.95、5.82、3.87、7.68화3.02,P치균＜0.05).결론 고혈압、당뇨병、고지혈증、흡연、남성화년령시복발성뇌경사적위험인소.
Objective To synthetically evaluate the risk factors of recurrent cerebral infarction in Chinese population.Methods The research literature on the risk factors of recurrent cerebral infarction from the domestic December 2011 published was collected through computers literature retrieval (China Academic Journal,VIP Chinese Science and Technology Academic Journal,Wanfang Database) and literature review.Meta-analysis method was used to synthetically and quantitatively analyze the risk factors of recurrent cerebral infarction reported in China.All of the data were analyzed by STATA 11.0 software.Results The total research literature was 216 studies,and 12 studies were enrolled in this study according to the inclusion and exclusion criteria.All case-control study.There were 1599 cases in case group,2566 cases in control group cumulatively.Meta analysis showed that the summary statistics of sex,hypertension,diabetes,hyperlipemia,smoking,age were 1.58 (1.04-2.39),2.66 (2.02-3.51),2.23 (1.70-2.93),2.22(1.48-3.32),1.94 (1.64-2.29),1.58 (0.55-2.60),respectively.There were significances in statistics (Z =2.16,6.95,5.82,3.87,7.68,3.02,respectively,P ＜ 0.05).Conclusion Hypertension,diabetes,hyperlipemia,smoking,male and age are all the risk factors of recurrent cerebral infarction.
