中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2014年
9期
25-27
,共3页
白亚菲%曲延明%王桂峰%刘静平%袁丽
白亞菲%麯延明%王桂峰%劉靜平%袁麗
백아비%곡연명%왕계봉%류정평%원려
面部%激素依赖性皮炎%高能红光%类人胶原蛋白敷料
麵部%激素依賴性皮炎%高能紅光%類人膠原蛋白敷料
면부%격소의뢰성피염%고능홍광%류인효원단백부료
Face%Corticosteroid addictive dermatitis%High-energy red light%Human-like collagen dressing
目的 观察高能红光联合类人胶原蛋白敷料治疗面部激素依赖性皮炎的疗效.方法 将83例面部激素依赖性皮炎患者按随机数字表法分为治疗组42例和对照组41例.所有患者均给予口服依巴斯汀10 mg,每日1次,维生素E霜每日2次治疗,对照组同时给予类人胶原蛋白敷料外敷,治疗第1周每日1次,之后3次/周.治疗组在对照组治疗基础上,联合高能红光照射面部10 min,2～3次/周,疗程共12周.分别于治疗第4,8及12周观察患者自觉症状、皮损情况及不良反应.结果 治疗第4周时,两组治疗有效率比较差异无统计学意义(P＞0.05).治疗第8,12周时,治疗组治疗有效率明显高于对照组[83.3％(35/42)比58.5％(24/41),90.5％(38/42)比65.9％(27/41)],差异均有统计学意义(P＜0.05).两组均未见任何不良反应.结论 高能红光联合类人胶原蛋白敷料治疗面部激素依赖性皮炎的疗效显著,安全可靠.
目的 觀察高能紅光聯閤類人膠原蛋白敷料治療麵部激素依賴性皮炎的療效.方法 將83例麵部激素依賴性皮炎患者按隨機數字錶法分為治療組42例和對照組41例.所有患者均給予口服依巴斯汀10 mg,每日1次,維生素E霜每日2次治療,對照組同時給予類人膠原蛋白敷料外敷,治療第1週每日1次,之後3次/週.治療組在對照組治療基礎上,聯閤高能紅光照射麵部10 min,2～3次/週,療程共12週.分彆于治療第4,8及12週觀察患者自覺癥狀、皮損情況及不良反應.結果 治療第4週時,兩組治療有效率比較差異無統計學意義(P＞0.05).治療第8,12週時,治療組治療有效率明顯高于對照組[83.3％(35/42)比58.5％(24/41),90.5％(38/42)比65.9％(27/41)],差異均有統計學意義(P＜0.05).兩組均未見任何不良反應.結論 高能紅光聯閤類人膠原蛋白敷料治療麵部激素依賴性皮炎的療效顯著,安全可靠.
목적 관찰고능홍광연합류인효원단백부료치료면부격소의뢰성피염적료효.방법 장83례면부격소의뢰성피염환자안수궤수자표법분위치료조42례화대조조41례.소유환자균급여구복의파사정10 mg,매일1차,유생소E상매일2차치료,대조조동시급여류인효원단백부료외부,치료제1주매일1차,지후3차/주.치료조재대조조치료기출상,연합고능홍광조사면부10 min,2～3차/주,료정공12주.분별우치료제4,8급12주관찰환자자각증상、피손정황급불량반응.결과 치료제4주시,량조치료유효솔비교차이무통계학의의(P＞0.05).치료제8,12주시,치료조치료유효솔명현고우대조조[83.3％(35/42)비58.5％(24/41),90.5％(38/42)비65.9％(27/41)],차이균유통계학의의(P＜0.05).량조균미견임하불량반응.결론 고능홍광연합류인효원단백부료치료면부격소의뢰성피염적료효현저,안전가고.
Objective To observe the efficacy of high-energy red light combined with human-like collagen dressing in treatment of facial corticosteroid addictive dermatitis.Methods Eighty-three patients with facial corticosteroid addictive dermatitis were divided into treatment group (42 cases) and control group (41 cases) by random digits table method.All patients in 2 groups were treated with ebastine 10 mg,once a day,and vitamin E cream,twice a day.At the same time,the patients in control group were given human-like collagen dressing,once a day in the first week,then 3 times/week.On the basis of control treatment,the patients in treatment group were irradiated with high-energy red light 10 min in face,2-3 times/week.The treatment of both groups lasted for 12 weeks.The symptoms,skin lesions and untoward reaction were observed after treatment of 4,8 and 12 weeks.Results After treatment of 4 weeks,there was no statistical difference in the effective rate between 2 groups (P ＞ 0.05).After treatment of 8 and 12 weeks,the effective rates in treatment group were significantly higher than those in control group [83.3％(35/42) vs.58.5％ (24/41),90.5％ (38/42) vs.65.9％ (27/41)],there were statistical differences (P ＜ 0.05).No untoward reaction was found in 2 groups.Conclusion High-energy red light combined with human-like collagen dressing is effective and safe in treatment of facial corticosteroid addictive dermatitis.
