中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2014年
10期
18-20
,共3页
卒中%危险因素%高同种半胱氨酸血症%脑白质高信号
卒中%危險因素%高同種半胱氨痠血癥%腦白質高信號
졸중%위험인소%고동충반광안산혈증%뇌백질고신호
Stroke%Risk factors%Hyperhomocysteinemia%White-matter hyperintensities
目的 探讨缺血性卒中患者脑白质高信号(WMHs)严重程度的相关危险因素.方法 回顾性分析急性缺血性卒中(AIS)患者的临床及影像学资料.结果 共纳入144例AIS患者,美国国立卫生研究院卒中量表评分(6.06±3.98)分,高血压89例,糖尿病32例,高脂血症43例,冠心病21例,心房颤动44例;大动脉粥样硬化型60例,穿支动脉疾病型8例,心源性卒中型64例,其他原因型4例,不明原因型8例.WMHs评分(7.81 ±4.93)分,中位评分6.5分.WMHs评分0～6分组72例,7～24分组72例,两组年龄、收缩压、高同型半胱氨酸血症(HHe)发生率比较差异有统计学意义[(61.08±12.45)岁比(72.03±10.13)岁、(149.40±25.43)mmHg(1 mmHg=0.133 kPa)比(159.19±23.63)mmHg、12.5％(9/72)比29.2％(21/72)](P＜0.05).多因素Logistic回归分析结果显示年龄和HHe是AIS患者WMHs严重程度的独立危险因素(P＜0.05).结论 年龄、HHe是AIS患者WMHs严重程度的独立危险因素.
目的 探討缺血性卒中患者腦白質高信號(WMHs)嚴重程度的相關危險因素.方法 迴顧性分析急性缺血性卒中(AIS)患者的臨床及影像學資料.結果 共納入144例AIS患者,美國國立衛生研究院卒中量錶評分(6.06±3.98)分,高血壓89例,糖尿病32例,高脂血癥43例,冠心病21例,心房顫動44例;大動脈粥樣硬化型60例,穿支動脈疾病型8例,心源性卒中型64例,其他原因型4例,不明原因型8例.WMHs評分(7.81 ±4.93)分,中位評分6.5分.WMHs評分0～6分組72例,7～24分組72例,兩組年齡、收縮壓、高同型半胱氨痠血癥(HHe)髮生率比較差異有統計學意義[(61.08±12.45)歲比(72.03±10.13)歲、(149.40±25.43)mmHg(1 mmHg=0.133 kPa)比(159.19±23.63)mmHg、12.5％(9/72)比29.2％(21/72)](P＜0.05).多因素Logistic迴歸分析結果顯示年齡和HHe是AIS患者WMHs嚴重程度的獨立危險因素(P＜0.05).結論 年齡、HHe是AIS患者WMHs嚴重程度的獨立危險因素.
목적 탐토결혈성졸중환자뇌백질고신호(WMHs)엄중정도적상관위험인소.방법 회고성분석급성결혈성졸중(AIS)환자적림상급영상학자료.결과 공납입144례AIS환자,미국국립위생연구원졸중량표평분(6.06±3.98)분,고혈압89례,당뇨병32례,고지혈증43례,관심병21례,심방전동44례;대동맥죽양경화형60례,천지동맥질병형8례,심원성졸중형64례,기타원인형4례,불명원인형8례.WMHs평분(7.81 ±4.93)분,중위평분6.5분.WMHs평분0～6분조72례,7～24분조72례,량조년령、수축압、고동형반광안산혈증(HHe)발생솔비교차이유통계학의의[(61.08±12.45)세비(72.03±10.13)세、(149.40±25.43)mmHg(1 mmHg=0.133 kPa)비(159.19±23.63)mmHg、12.5％(9/72)비29.2％(21/72)](P＜0.05).다인소Logistic회귀분석결과현시년령화HHe시AIS환자WMHs엄중정도적독립위험인소(P＜0.05).결론 년령、HHe시AIS환자WMHs엄중정도적독립위험인소.
Objective To investigate the risk factors for the severity of white-matter hyperintensities (WMHs) in ischemic stroke patients.Methods Clinical and radiological data of acute ischemic stroke (AIS) patients were analyzed retrospectively.Results A total of 144 patients with AIS were enrolled including 89 cases of hypertension,32 eases of diabetes,43 cases of hyperlipidemia,21 cases of coronary heart disease,44 cases of atrial fibrillation; 60 cases of large artery atherosclerosis,8 cases of perforating artery disease,64 cases of cardiogenic stroke type,4 cases of other causes type and 8 cases of unexplained.U.S.national institutes of health stroke scale score was (6.06 ± 3.98) scores.WMHs score was (7.81 ± 4.93) scores,and median score was 6.5 scores.WMHs score 0-6 scores group had 72 cases,and 7-24 scores group had 72 cases.The age,systolic pressure,hyperhomocysteinemia(HHe) incidence in 0-6 scores group was statistically lower than that in 7-24 scores group [(61.08 ± 12.45) years vs.(72.03 ± 10.13) years,(149.40 ±25.43) mmHg (1 mmHg =0.133 kPa) vs.(159.19 ±23.63) mmHg,12.5％(9/72) vs.29.2％ (21/72)] (P ＜ 0.05).Logistic regression analysis showed that age and HHe was independent risk factor for the severity of WMHs in AIS patients (P ＜ 0.05).Conclusion Age and HHe is independent risk factor for the severity of WMHs in AIS patients.
