中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2014年
13期
42-43
,共2页
冠状动脉疾病%高半胱氨酸%胱抑素C
冠狀動脈疾病%高半胱氨痠%胱抑素C
관상동맥질병%고반광안산%광억소C
Coronary artery disease%Homocysteine%Cystatin C
目的 探讨血清同型半胱氨酸(Hcy)、胱抑素C(CysC)检测在冠心病预防、诊断及治疗中的临床价值.方法 200例冠心病患者中急性心肌梗死(AMI) 50例(AMI组),不稳定型心绞痛(UAP) 85例(UAP组),稳定型心绞痛(SAP) 65例(SAP组).选取同期健康体检者120例作为健康对照组.检测血清Hcy及CysC水平,并进行比较.结果 AMI组、UAP组、SAP组血清Hcy及CysC水平显著高于健康对照组[Hcy:(22.35±8.18)、(16.54±7.56)、(14.52±6.38)μmol/L比(9.35±3.23)μmol/L; CysC:(1.32±0.27)、(1.88±0.66)、(1.19±0.46) mg/L比(0.80±0.33) mg/L],差异有统计学意义(P＜0.01).AMI组血清Hcy水平显著高于UAP组、SAP组[(22.35±8.18)μmol/L比(16.54±7.56)、(14.52±6.38)μmol/L],差异有统计学意义(P＜0.01).结论 血清Hey及CysC水平与冠心病关系密切,且Hcy水平随着冠心病程度的加重而增加,检测Hcy及CysC对冠心病的预防、诊断及治疗具有一定的临床价值.
目的 探討血清同型半胱氨痠(Hcy)、胱抑素C(CysC)檢測在冠心病預防、診斷及治療中的臨床價值.方法 200例冠心病患者中急性心肌梗死(AMI) 50例(AMI組),不穩定型心絞痛(UAP) 85例(UAP組),穩定型心絞痛(SAP) 65例(SAP組).選取同期健康體檢者120例作為健康對照組.檢測血清Hcy及CysC水平,併進行比較.結果 AMI組、UAP組、SAP組血清Hcy及CysC水平顯著高于健康對照組[Hcy:(22.35±8.18)、(16.54±7.56)、(14.52±6.38)μmol/L比(9.35±3.23)μmol/L; CysC:(1.32±0.27)、(1.88±0.66)、(1.19±0.46) mg/L比(0.80±0.33) mg/L],差異有統計學意義(P＜0.01).AMI組血清Hcy水平顯著高于UAP組、SAP組[(22.35±8.18)μmol/L比(16.54±7.56)、(14.52±6.38)μmol/L],差異有統計學意義(P＜0.01).結論 血清Hey及CysC水平與冠心病關繫密切,且Hcy水平隨著冠心病程度的加重而增加,檢測Hcy及CysC對冠心病的預防、診斷及治療具有一定的臨床價值.
목적 탐토혈청동형반광안산(Hcy)、광억소C(CysC)검측재관심병예방、진단급치료중적림상개치.방법 200례관심병환자중급성심기경사(AMI) 50례(AMI조),불은정형심교통(UAP) 85례(UAP조),은정형심교통(SAP) 65례(SAP조).선취동기건강체검자120례작위건강대조조.검측혈청Hcy급CysC수평,병진행비교.결과 AMI조、UAP조、SAP조혈청Hcy급CysC수평현저고우건강대조조[Hcy:(22.35±8.18)、(16.54±7.56)、(14.52±6.38)μmol/L비(9.35±3.23)μmol/L; CysC:(1.32±0.27)、(1.88±0.66)、(1.19±0.46) mg/L비(0.80±0.33) mg/L],차이유통계학의의(P＜0.01).AMI조혈청Hcy수평현저고우UAP조、SAP조[(22.35±8.18)μmol/L비(16.54±7.56)、(14.52±6.38)μmol/L],차이유통계학의의(P＜0.01).결론 혈청Hey급CysC수평여관심병관계밀절,차Hcy수평수착관심병정도적가중이증가,검측Hcy급CysC대관심병적예방、진단급치료구유일정적림상개치.
Objective To investigate the clinical value of serum homocysteine (Hcy),Cystatin C (CysC) detection in coronary heart disease prevention,diagnosis and treatment.Methods A total of 200 cases of coronary heart disease patients including 50 cases of acute myocardiac infarction (AMI) (AMI group),85 cases of unstable angina pectoris (UAP)(UAP group.) and 65 cases of stable angina pectoris (SAP) (SAP group) were selected,and 120 cases of healthy controls were selected as control group.The serum levels of Hcy and CysC were detected and compared.Results The serum levels of Hcy and CysC in AMI group,UAP group and SAP group were significandy higher than those in control group[Hcy:(22.35 ± 8.18),(16.54±7.56),(14.52±6.38) μmol/Lvs.(9.35±3.23) μmol/L; CysC:(1.32±0.27),(1.88± 0.66),(1.19 ± 0.46) mg/L vs.(0.80 ± 0.33) mg/L],and there were significant differences between two groups (P＜ 0.01).The serum level of Hcy in AMI group was higher than that in UAP group and SAP group [(22.35 ± 8.18) μ mol/L vs.(16.54 ± 7.56),(14.52 ± 6.38) μ mol/L],and there was significant difference (P ＜ 0.01).Conclusions The relationship between Hcy,CysC level and coronary heart disease is close,and Hcy levels increase with increasing degree of coronary heart disease.Detection of Hcy and CysC has some clinical value on prevention,diagnosis,treatment of coronary heart disease.
