中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2014年
16期
40-42
,共3页
梗塞,大脑中动脉%脑白质疏松症%高血压%24 h尿微量白蛋白
梗塞,大腦中動脈%腦白質疏鬆癥%高血壓%24 h尿微量白蛋白
경새,대뇌중동맥%뇌백질소송증%고혈압%24 h뇨미량백단백
Infarction,middle cerebral artery%Leukoaraiosis%Hypertension%24 h microalbuminuria
目的 探讨脑梗死患者轻度肾功能损伤的相关危险因素.方法 选择2012年6月至2013年6月收治的脑梗死患者150例,均行磁共振检查,详细记录患者的临床资料,并检测24 h尿微量白蛋白(mALB),评估肾功能.根据mALB分为肾功能正常组(105例)及轻度肾功能损伤组(45例).比较两组临床危险因素,并进行多因素回归分析.结果 轻度肾功能损伤组患者年龄大于肾功能正常组[(67.04±9.37)岁比(63.01±11.18)岁],高血压、多发性腔隙性脑梗死发生率高于肾功能正常组[57.8％(26/45)比33.3％(35/105)、57.8％(26/45)比22.9％(24/105)],脑白质疏松等级高于肾功能正常组,差异均有统计学意义(P＜0.05或＜0.01).通过二分类的Logistic回归分析发现,高血压(OR=1.041,P=0.045)、脑白质疏松症(OR=2.048,P=0.000)是脑梗死患者轻度肾功能损伤的独立危险因素.结论 脑梗死患者轻度肾功能损伤发生率较高,与高血压及脑白质疏松症密切相关.早期检测脑梗死患者24 h mALB有重要的临床意义.
目的 探討腦梗死患者輕度腎功能損傷的相關危險因素.方法 選擇2012年6月至2013年6月收治的腦梗死患者150例,均行磁共振檢查,詳細記錄患者的臨床資料,併檢測24 h尿微量白蛋白(mALB),評估腎功能.根據mALB分為腎功能正常組(105例)及輕度腎功能損傷組(45例).比較兩組臨床危險因素,併進行多因素迴歸分析.結果 輕度腎功能損傷組患者年齡大于腎功能正常組[(67.04±9.37)歲比(63.01±11.18)歲],高血壓、多髮性腔隙性腦梗死髮生率高于腎功能正常組[57.8％(26/45)比33.3％(35/105)、57.8％(26/45)比22.9％(24/105)],腦白質疏鬆等級高于腎功能正常組,差異均有統計學意義(P＜0.05或＜0.01).通過二分類的Logistic迴歸分析髮現,高血壓(OR=1.041,P=0.045)、腦白質疏鬆癥(OR=2.048,P=0.000)是腦梗死患者輕度腎功能損傷的獨立危險因素.結論 腦梗死患者輕度腎功能損傷髮生率較高,與高血壓及腦白質疏鬆癥密切相關.早期檢測腦梗死患者24 h mALB有重要的臨床意義.
목적 탐토뇌경사환자경도신공능손상적상관위험인소.방법 선택2012년6월지2013년6월수치적뇌경사환자150례,균행자공진검사,상세기록환자적림상자료,병검측24 h뇨미량백단백(mALB),평고신공능.근거mALB분위신공능정상조(105례)급경도신공능손상조(45례).비교량조림상위험인소,병진행다인소회귀분석.결과 경도신공능손상조환자년령대우신공능정상조[(67.04±9.37)세비(63.01±11.18)세],고혈압、다발성강극성뇌경사발생솔고우신공능정상조[57.8％(26/45)비33.3％(35/105)、57.8％(26/45)비22.9％(24/105)],뇌백질소송등급고우신공능정상조,차이균유통계학의의(P＜0.05혹＜0.01).통과이분류적Logistic회귀분석발현,고혈압(OR=1.041,P=0.045)、뇌백질소송증(OR=2.048,P=0.000)시뇌경사환자경도신공능손상적독립위험인소.결론 뇌경사환자경도신공능손상발생솔교고,여고혈압급뇌백질소송증밀절상관.조기검측뇌경사환자24 h mALB유중요적림상의의.
Objective To investigate the risk factors of mild renal impairment in cerebral infarction patients.Methods One hundred and fifty patients with cerebral infarction were enrolled from June 2012 to June 2013,and all patients received cranial magnetic resonance imaging at the first week.The clinical data of patients were recorded in detail,24 h microalbuminuria (mALB) was detected,renal function was assessed.According to mALB,the patients were divided into normal renal function group (105 cases) and mild renal dysfunction group (45 cases).Clinical risk factors between 2 groups were compared,and multivariate regression analysis was done.Results Age in mild renal dysfunction group was greater than that in normal renal function group [(67.04 ±9.37) years vs.(63.01 ± 11.18) years],the incidence of hypertension and multiple lacunar infarction were higher than those in normal renal function group[57.8％ (26/45) vs.33.3％ (35/105),57.8％ (26/45) vs.22.9％ (24/105)],leukoaraiosis grade was higher than that in normal renal function group,there were significant differences (P ＜ 0.05 or ＜ 0.01).Logistic regression analysis found that hypertension (OR =1.04 1,P =0.045) and leukoaraiosis (OR =2.048,P =0.000) were independent risk factors for cerebral infarction patients with mild renal impairment.Conclusions The incidence of mild renal impairment is higher in cerebral infarction patients,and is closely related to hypertension and leukoariosis.Early detection of 24 h mALB in cerebral infarction patients has important clinical significance.
