中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2014年
16期
55-57
,共3页
胰岛素输注系统%糖尿病,2型%高龄
胰島素輸註繫統%糖尿病,2型%高齡
이도소수주계통%당뇨병,2형%고령
Insulin infusion systems%Diabetes mellitus,type 2%Advanced age
目的 比较胰岛素泵持续皮下输注胰岛素与多次皮下注射胰岛素对重症高龄2型糖尿病患者的疗效与安全性.方法 将37例在重症监护室(ICU)住院的重症高龄2型糖尿病患者按随机数字表法分为观察组(19例)和对照组(18例),观察组用胰岛素泵持续皮下输注赖脯胰岛素,对照组用赖脯胰岛素三餐前及甘精胰岛素晚上睡前常规皮下注射,两组患者及家属均给予糖尿病教育、根据病情合适的糖尿病饮食,比较治疗前后两组患者的血糖变化、胰岛素用量、血糖控制达标时间、低血糖发生率及住院时间.结果 治疗后观察组空腹血糖为(7.2±1.2)mmo1/L,餐后2h血糖为(9.4±1.2) mmol/L,睡前血糖为(9.4±1.3) mmol/L,对照组分别为(8.5±3.0)、(10.0±2.4)、(10.2±2.4)mmol/L,治疗后两组患者空腹血糖、餐后2h血糖及睡前血糖均较治疗前显著下降,且两组治疗后比较差异有统计学意义(P＜0.05).观察组患者血糖控制达标时间为(5.4±2.5)d,胰岛素用量为(43±9)U/d,而对照组分别为(12.8±3.8)d、(55±10)U/d,两组比较差异有统计学意义(P＜0.05).观察组未见低血糖发生.结论 胰岛素泵持续皮下输注胰岛素与多次皮下注射胰岛素对重症高龄2型糖尿病均具有较好的疗效与安全性,且胰岛素泵持续皮下输注胰岛素更利于此类患者血糖控制及改善病情.
目的 比較胰島素泵持續皮下輸註胰島素與多次皮下註射胰島素對重癥高齡2型糖尿病患者的療效與安全性.方法 將37例在重癥鑑護室(ICU)住院的重癥高齡2型糖尿病患者按隨機數字錶法分為觀察組(19例)和對照組(18例),觀察組用胰島素泵持續皮下輸註賴脯胰島素,對照組用賴脯胰島素三餐前及甘精胰島素晚上睡前常規皮下註射,兩組患者及傢屬均給予糖尿病教育、根據病情閤適的糖尿病飲食,比較治療前後兩組患者的血糖變化、胰島素用量、血糖控製達標時間、低血糖髮生率及住院時間.結果 治療後觀察組空腹血糖為(7.2±1.2)mmo1/L,餐後2h血糖為(9.4±1.2) mmol/L,睡前血糖為(9.4±1.3) mmol/L,對照組分彆為(8.5±3.0)、(10.0±2.4)、(10.2±2.4)mmol/L,治療後兩組患者空腹血糖、餐後2h血糖及睡前血糖均較治療前顯著下降,且兩組治療後比較差異有統計學意義(P＜0.05).觀察組患者血糖控製達標時間為(5.4±2.5)d,胰島素用量為(43±9)U/d,而對照組分彆為(12.8±3.8)d、(55±10)U/d,兩組比較差異有統計學意義(P＜0.05).觀察組未見低血糖髮生.結論 胰島素泵持續皮下輸註胰島素與多次皮下註射胰島素對重癥高齡2型糖尿病均具有較好的療效與安全性,且胰島素泵持續皮下輸註胰島素更利于此類患者血糖控製及改善病情.
목적 비교이도소빙지속피하수주이도소여다차피하주사이도소대중증고령2형당뇨병환자적료효여안전성.방법 장37례재중증감호실(ICU)주원적중증고령2형당뇨병환자안수궤수자표법분위관찰조(19례)화대조조(18례),관찰조용이도소빙지속피하수주뢰포이도소,대조조용뢰포이도소삼찬전급감정이도소만상수전상규피하주사,량조환자급가속균급여당뇨병교육、근거병정합괄적당뇨병음식,비교치료전후량조환자적혈당변화、이도소용량、혈당공제체표시간、저혈당발생솔급주원시간.결과 치료후관찰조공복혈당위(7.2±1.2)mmo1/L,찬후2h혈당위(9.4±1.2) mmol/L,수전혈당위(9.4±1.3) mmol/L,대조조분별위(8.5±3.0)、(10.0±2.4)、(10.2±2.4)mmol/L,치료후량조환자공복혈당、찬후2h혈당급수전혈당균교치료전현저하강,차량조치료후비교차이유통계학의의(P＜0.05).관찰조환자혈당공제체표시간위(5.4±2.5)d,이도소용량위(43±9)U/d,이대조조분별위(12.8±3.8)d、(55±10)U/d,량조비교차이유통계학의의(P＜0.05).관찰조미견저혈당발생.결론 이도소빙지속피하수주이도소여다차피하주사이도소대중증고령2형당뇨병균구유교호적료효여안전성,차이도소빙지속피하수주이도소경리우차류환자혈당공제급개선병정.
Objective To compare the clinical efficacy and safety of continuous subcutaneous insulin infusion (CSII) and multiple subcutaneous insulin injection (MSII) in elderly patients with severe type 2 diabetes.Methods Thirty-seven elderly patients with severe type 2 diabetes in the hospital intensive care unit (ICU) were divided into observation group (19 cases) and control group (18 cases) by random number table method.The observation group was treated with continuous subcutaneous insulin recombinant human insulin lispro injection,and control group was treated with recombinant human insulin lispro injection before meals and at bedtime routine insulin glargine subcutaneous injection.Two groups of patients and their families were given diabetes education.Changes in blood glucose,insulin dosage,blood glucose control standard time,rate of hypoglycemia and hospitalization time between 2 groups before and after treatment were compared.Results After treatment,fasting blood glucose in observation group was (7.2 ± 1.2) mmol/L,2 hour postprandial blood glucose was (9.4 ± 1.2) mmol/L,bedtime blood glucose was (9.4 ± 1.3) mmol/L; which in control group was (8.5 ± 3.0),(10.0 ± 2.4),(10.2 ± 2.4)mmol/L respectively.Fasting blood glucose,2 hour postprandial blood glucose and bedtime blood glucose significantly decreased after treatment in two groups,but there was significant difference between 2 groups (P ＜ 0.05).Blood glucose control standard time in observation group was (5.4 ± 2.5) d,insulin dosage was (43 ± 9) U/d,in control group was (12.8 ± 3.8) d,(55 ± 10) U/d respectively,and there was significant difference (P ＜ 0.05).Observation group had no hypoglycemia.Conclusion CSII for elderly patients with severe type 2 diabetes has better curative effect and security than MSII,and is more conducive to the control of blood glucose and the improvement of the condition.
