中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2014年
17期
21-23
,共3页
神经胶质瘤%盐酸戊乙奎醚%围手术期医护%手术后并发症
神經膠質瘤%鹽痠戊乙奎醚%圍手術期醫護%手術後併髮癥
신경효질류%염산무을규미%위수술기의호%수술후병발증
Glioma%Penehyclidine hydrochloride%Perioperative care%Postoperative complications
目的 探讨术前肌肉注射盐酸戊乙奎醚对预防脑胶质瘤术后患者肺部并发症发生的影响.方法 择期行脑胶质瘤患者70例,年龄30 ～ 69岁,体质量50～80 kg,ASA分级Ⅱ或Ⅲ级,采用随机数字表法,将其分为两组(每组35例):对照组(C组),盐酸戊乙奎醚组(W组).两组麻醉诱导以及麻醉维持方法相同.W组于全身麻醉诱导前30 min肌肉注射盐酸戊乙奎醚20μg/kg(2 ml),C组以等容量0.9％氯化钠替代.于术后72 h内记录患者肺部并发症发生情况.结果 C组和W组肺部并发症发生率分别为28.6％(10/35)和11.4％(4/35).与C组比较,W组肺部并发症发生率降低(P＜0.05).结论 术前肌肉注射盐酸戊乙奎醚20μg/kg可预防脑胶质瘤术后患者肺部并发症的发生.
目的 探討術前肌肉註射鹽痠戊乙奎醚對預防腦膠質瘤術後患者肺部併髮癥髮生的影響.方法 擇期行腦膠質瘤患者70例,年齡30 ～ 69歲,體質量50～80 kg,ASA分級Ⅱ或Ⅲ級,採用隨機數字錶法,將其分為兩組(每組35例):對照組(C組),鹽痠戊乙奎醚組(W組).兩組痳醉誘導以及痳醉維持方法相同.W組于全身痳醉誘導前30 min肌肉註射鹽痠戊乙奎醚20μg/kg(2 ml),C組以等容量0.9％氯化鈉替代.于術後72 h內記錄患者肺部併髮癥髮生情況.結果 C組和W組肺部併髮癥髮生率分彆為28.6％(10/35)和11.4％(4/35).與C組比較,W組肺部併髮癥髮生率降低(P＜0.05).結論 術前肌肉註射鹽痠戊乙奎醚20μg/kg可預防腦膠質瘤術後患者肺部併髮癥的髮生.
목적 탐토술전기육주사염산무을규미대예방뇌효질류술후환자폐부병발증발생적영향.방법 택기행뇌효질류환자70례,년령30 ～ 69세,체질량50～80 kg,ASA분급Ⅱ혹Ⅲ급,채용수궤수자표법,장기분위량조(매조35례):대조조(C조),염산무을규미조(W조).량조마취유도이급마취유지방법상동.W조우전신마취유도전30 min기육주사염산무을규미20μg/kg(2 ml),C조이등용량0.9％록화납체대.우술후72 h내기록환자폐부병발증발생정황.결과 C조화W조폐부병발증발생솔분별위28.6％(10/35)화11.4％(4/35).여C조비교,W조폐부병발증발생솔강저(P＜0.05).결론 술전기육주사염산무을규미20μg/kg가예방뇌효질류술후환자폐부병발증적발생.
Objective To evaluate the efficacy of penehyclidine hydrochloride for prevention of postoperative pulmonary complications (PPC) in patients undergoing brain glioma resection.Methods Seventy ASA class Ⅱ-Ⅲ patients,aged 30-69 years,weighing 50-80 kg,undergoing brain glioma resection,were divided into 2 groups by random digits table method:control group (group C,35 patients) and penehyclidine hydrochloride group (group W,35 patients).The patients in two groups were given the same methods of anesthesia induced and maintain.The patients in group W were given penehyclidine hydrochloride[20 μ g/kg(2 ml)] before anesthesia induced 30 min,meanwhile the patients in group C were given equal volume of saline.The occurrence of PPC was recorded within 72 h after operation and compared between two groups.Results The incidence of PPC in group W was significantly lower than that in group C [11.4％ (4/35) vs.28.6％ (10/35)] (P ＜ 0.05).Conclusion Intramuscular of penehyclidine hydrochloride 20 μ g/kg before operation can prevent the occurrence of PPC in patients undergoing brain glioma resection.
