中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2014年
20期
29-31
,共3页
肉瘤,滑膜%肺%诊断
肉瘤,滑膜%肺%診斷
육류,활막%폐%진단
Sarcoma,synovial%Lung%Diagnosis
目的 探讨提高肺滑膜肉瘤诊断、治愈率的方法.方法 选择1例肺滑膜肉瘤患者,同时结合2012年10月中国期刊全文数据库收录发表的80例资料较为完整的肺原发性滑膜肉瘤患者进行回顾性研究,分析其主要临床表现、影像学特点,根据病理学、免疫组化特点及分子生物学对其进行诊断及鉴别诊断,以减少误诊.结果 81例肺原发性滑膜肉瘤患者中,男40例,女41例.主要临床表现有胸痛、呼吸困难、咯血及咳嗽.个别病例无任何不适.全部病例均进行手术治疗.术前均未确诊,最终依赖病理、免疫组化支持诊断.结论 肺原发性滑膜肉瘤临床表现不一,影像学检查具有相对特征表现,易与其他肺部肿瘤或炎性反应混淆;确诊需依靠病理、免疫组化和融合基因检测.手术切除是主要的治疗方法,切除不完全者预后差.
目的 探討提高肺滑膜肉瘤診斷、治愈率的方法.方法 選擇1例肺滑膜肉瘤患者,同時結閤2012年10月中國期刊全文數據庫收錄髮錶的80例資料較為完整的肺原髮性滑膜肉瘤患者進行迴顧性研究,分析其主要臨床錶現、影像學特點,根據病理學、免疫組化特點及分子生物學對其進行診斷及鑒彆診斷,以減少誤診.結果 81例肺原髮性滑膜肉瘤患者中,男40例,女41例.主要臨床錶現有胸痛、呼吸睏難、咯血及咳嗽.箇彆病例無任何不適.全部病例均進行手術治療.術前均未確診,最終依賴病理、免疫組化支持診斷.結論 肺原髮性滑膜肉瘤臨床錶現不一,影像學檢查具有相對特徵錶現,易與其他肺部腫瘤或炎性反應混淆;確診需依靠病理、免疫組化和融閤基因檢測.手術切除是主要的治療方法,切除不完全者預後差.
목적 탐토제고폐활막육류진단、치유솔적방법.방법 선택1례폐활막육류환자,동시결합2012년10월중국기간전문수거고수록발표적80례자료교위완정적폐원발성활막육류환자진행회고성연구,분석기주요림상표현、영상학특점,근거병이학、면역조화특점급분자생물학대기진행진단급감별진단,이감소오진.결과 81례폐원발성활막육류환자중,남40례,녀41례.주요림상표현유흉통、호흡곤난、각혈급해수.개별병례무임하불괄.전부병례균진행수술치료.술전균미학진,최종의뢰병리、면역조화지지진단.결론 폐원발성활막육류림상표현불일,영상학검사구유상대특정표현,역여기타폐부종류혹염성반응혼효;학진수의고병리、면역조화화융합기인검측.수술절제시주요적치료방법,절제불완전자예후차.
Objective To investigate the way of improving the diagnosis and cure rate of pulmonary synovial sarcoma.Methods One case of pulmonary synovial sarcoma was selected,at the same time accompanied with 80 cases of pulmonary synovial sarcoma with complete data referenced from China Journal Full-text Database on October 2012 were retrospectively studied.The main clinical manifestations,imaging characteristics were analyszed.According to the pathology,immunohisochemistry and molecular biology for diagnosis and discrimination,in order to reduce the misdiagnosis.Results All of 81 patients,40 male cases and 41 female cases,the main clinical manifestations were chest pain,difficult breathing,hemoptysis and cough.In individual cases without any discomfort.All cases had not been accurately diagnosed before surgery.Ultimately diagnosis of patients depend on histopathology and immunohistochemistry.Conclusions Pulmonary synovial sarcoma shows different clinical symptoms but specific imaging characteristic and maybe confused with other pulmonary tumors or inflammation.Histopathological,immunophenotypic and fusion gene detection is the mainly technics for diagnosis.Surgery is the primary therapy,patients undergoing uncompletely resection have a poor prognosis.
