药物不良反应杂志
藥物不良反應雜誌
약물불량반응잡지
ADVERSE DRUG REACTIONS JOURNAL
2013年
1期
48-49
,共2页
陈文静%南善姬%宋春伶%闫伟
陳文靜%南善姬%宋春伶%閆偉
진문정%남선희%송춘령%염위
卡马西平%偏瘫%偏身感觉障碍
卡馬西平%偏癱%偏身感覺障礙
잡마서평%편탄%편신감각장애
Carbamazepine%Hemiplegia%Hemidysesthesia
1例51岁女性三叉神经痛患者口服卡马西平(0.2g,3次/d)治疗约1年,因疼痛加重1d内累积服用卡马西平2 g,第2天在口服卡马西平0.4g之后出现头晕、视物模糊和右侧肢体麻木、无力,遂入院.入院后体格检查:右侧中枢性面舌瘫,咽反射消失,右侧肢体肌力为Ⅳ级,右侧面部及肢体痛觉减退.头部磁共振成像和弥散加权磁共振成像检查未见异常.停用卡马西平,同时给予改善循环药物治疗.4d后患者完全恢复正常.
1例51歲女性三扠神經痛患者口服卡馬西平(0.2g,3次/d)治療約1年,因疼痛加重1d內纍積服用卡馬西平2 g,第2天在口服卡馬西平0.4g之後齣現頭暈、視物模糊和右側肢體痳木、無力,遂入院.入院後體格檢查:右側中樞性麵舌癱,嚥反射消失,右側肢體肌力為Ⅳ級,右側麵部及肢體痛覺減退.頭部磁共振成像和瀰散加權磁共振成像檢查未見異常.停用卡馬西平,同時給予改善循環藥物治療.4d後患者完全恢複正常.
1례51세녀성삼차신경통환자구복잡마서평(0.2g,3차/d)치료약1년,인동통가중1d내루적복용잡마서평2 g,제2천재구복잡마서평0.4g지후출현두훈、시물모호화우측지체마목、무력,수입원.입원후체격검사:우측중추성면설탄,인반사소실,우측지체기력위Ⅳ급,우측면부급지체통각감퇴.두부자공진성상화미산가권자공진성상검사미견이상.정용잡마서평,동시급여개선순배약물치료.4d후환자완전회복정상.
A 51-year-old female patient with trigeminal neuralgia received carbamazepine 0.2 g thrice daily by mouth for about one year.She took carbamazepine at a cumulative dose of 2 g within one day for aggravated pain.On the second day,the patient developed dizziness,blurred vision,numbness and weakness in her right extremities after taking carbamazepine 0.4 g,and then she was admitted into hospital.Physical examination showed the following results:right central facial and tongue nerve paralysis,absence of pharyngeal reflex,muscle strength of grade 4 in her right limb,hypalgesia in her right side of face and limbs.Examination of cranial magnetic resonance imaging and diffusion-weighted magnetic resonance imaging showed no abnormal changes.Carbamazepine was stopped and drug for improving circulation was given.Four days later,the patient recovered completely.