药物不良反应杂志
藥物不良反應雜誌
약물불량반응잡지
ADVERSE DRUG REACTIONS JOURNAL
2013年
1期
52-53
,共2页
过敏反应%休克%苯磺顺阿曲库铵
過敏反應%休剋%苯磺順阿麯庫銨
과민반응%휴극%분광순아곡고안
Anaphylaxis%Shock%Cisatracurium besilate
1例68岁男性患者因颈椎病、椎间盘突出、椎管狭窄、脊髓压迫症、颈髓损伤行手术治疗.手术开始后静脉注射地塞米松10 mg、苯磺顺阿曲库铵2 mg和血凝酶2U.5 min后患者血压降至50/40 mm Hg(1 mm Hg=0.133 kPa),心率130次/min,脉搏血氧饱和度0.90,四肢及躯干出现红色皮疹.立即给予肾上腺素、甲泼尼龙、去氧肾上腺素等,同时放弃手术,缝合手术切口.10 min后患者血压升至110/65 mm Hg,生命体征渐趋稳定.3d后再次手术,手术开始后5h静脉注射苯磺顺阿曲库铵5 mg.5 min后患者再次出现血压下降(55/40 mm Hg),四肢及躯干出现红色皮疹.给予肾上腺素及甲泼尼龙素等抢救,20 min后血压恢复至105 ~115/65~70 mm Hg,lh后手术顺利完成.
1例68歲男性患者因頸椎病、椎間盤突齣、椎管狹窄、脊髓壓迫癥、頸髓損傷行手術治療.手術開始後靜脈註射地塞米鬆10 mg、苯磺順阿麯庫銨2 mg和血凝酶2U.5 min後患者血壓降至50/40 mm Hg(1 mm Hg=0.133 kPa),心率130次/min,脈搏血氧飽和度0.90,四肢及軀榦齣現紅色皮疹.立即給予腎上腺素、甲潑尼龍、去氧腎上腺素等,同時放棄手術,縫閤手術切口.10 min後患者血壓升至110/65 mm Hg,生命體徵漸趨穩定.3d後再次手術,手術開始後5h靜脈註射苯磺順阿麯庫銨5 mg.5 min後患者再次齣現血壓下降(55/40 mm Hg),四肢及軀榦齣現紅色皮疹.給予腎上腺素及甲潑尼龍素等搶救,20 min後血壓恢複至105 ~115/65~70 mm Hg,lh後手術順利完成.
1례68세남성환자인경추병、추간반돌출、추관협착、척수압박증、경수손상행수술치료.수술개시후정맥주사지새미송10 mg、분광순아곡고안2 mg화혈응매2U.5 min후환자혈압강지50/40 mm Hg(1 mm Hg=0.133 kPa),심솔130차/min,맥박혈양포화도0.90,사지급구간출현홍색피진.립즉급여신상선소、갑발니룡、거양신상선소등,동시방기수술,봉합수술절구.10 min후환자혈압승지110/65 mm Hg,생명체정점추은정.3d후재차수술,수술개시후5h정맥주사분광순아곡고안5 mg.5 min후환자재차출현혈압하강(55/40 mm Hg),사지급구간출현홍색피진.급여신상선소급갑발니룡소등창구,20 min후혈압회복지105 ~115/65~70 mm Hg,lh후수술순리완성.
A 68-year-old man underwent operation for cervical spondylopathy,herniated disk,spinal canal stenosis,compressive myelopathy,and cervical spinal cord injury.After the start of the operation,dexamethasone 10 mg,cisatracurium besilate 2 mg,and hemocoagulase 2 U were given intravenously.Five minutes later,the patient's blood pressure fell to 50/40 mm Hg,his heart rate was 130 beats/min and oxygen saturation was 0.90.He developed red rashes on his limbs and trunk.Phenylephrine,methylprednisolone,and diphenhydramine were given immediately.Meanwhile the operation was given up and surgical incision was sutured.Ten minutes later,his blood pressure rose to 110/65 mm Hg and vital signs became more stable.Three days later,he underwent operation again and,five hours after the start of the operation,he received Ⅳ cisatracurium besilate 5 mg.Five minutes later,the patient's blood pressure fell again (55/40 mm Hg) and red rashes appeared on his limbs and trunk.Phenylephrine,methylprednisolone,and other resuscitative measures were administered.Twenty minutes later,his blood pressure returned to 105-115/65-70 mm Hg and,one hour later,his surgery was completed uneventfully.