CAJ | 학술논문

1例64岁男性患者因肺部感染给予莫西沙星0.4g,1次/d静脉滴注,并口服肺力咳胶囊及西替利嗪.第2天,血生化检查示丙氨酸转氨酶(ALT) 49 U/L、天冬氨酸转氨酶(AST)30 U/L.第5天ALT及AST分别升至166 U/L、53 U/L.第9天停用莫西沙星,改为左氧氟沙星0.5g,1次/d口服,并行保肝治疗,肺力咳胶囊及西替利嗪按原剂量继续服用.第10天ALT 111 U/L,AST28 U/L;第13天ALT 77 U/L,AST 23 U/L.2个月后肝功能恢复正常(ALT28 U/L,AST 21 U/L).
1례64세남성환자인폐부감염급여막서사성0.4g,1차/d정맥적주,병구복폐력해효낭급서체리진.제2천,혈생화검사시병안산전안매(ALT) 49 U/L、천동안산전안매(AST)30 U/L.제5천ALT급AST분별승지166 U/L、53 U/L.제9천정용막서사성,개위좌양불사성0.5g,1차/d구복,병행보간치료,폐력해효낭급서체리진안원제량계속복용.제10천ALT 111 U/L,AST28 U/L;제13천ALT 77 U/L,AST 23 U/L.2개월후간공능회복정상(ALT28 U/L,AST 21 U/L).
A 64-year-old man received an Ⅳ infusion of moxifloxacin 0.4 g once daily with concomitant use of oral Feilike capsules (肺力咳胶囊)and oral cetirizine for pulmonary infection.On day 2,biochemical tests showed an alanine aminotransferase (ALT) level of 49 U/L and an aspartate aminotransferase (AST) level of 30 U/L.On day 5,the values of ALT and AST rose to 166 U/L and 53 U/L,respectively.On day 9,moxifloxacin was withdrawn and changed to levofloxacin 0.5 g once daily orally.Meanwhile,liver-protective treatment was given and Feilike capsules and cetirizine were continued at original dosage.On day 10,the values of ALT and AST were respectively 111 U/L and 28 U/L,and on day 13,the value of ALT was 77 U/L and the value of AST was 23 U/L.Two months later,hepatic function returned to normal (an ALT level of 28 U/L and an AST level of 21 U/L).